Objective To perform a systematic review and meta-analysis to determine whether fluid and
imaging astrocyte biomarkers are altered in Alzheimer disease (AD). Methods PubMed and …

S100B is a calcium‐binding peptide produced mainly by astrocytes that exert paracrine and
autocrine effects on neurons and glia. Some knowledge has been acquired from in vitro and …

Astrocyte pathology occurs in association with Alzheimer's disease (AD) and in brain
ageing, but is poorly characterised. We sought to define the detailed cellular pathology of …

Certain cytokines, the prototype being the highly pleiotropic TNF, have many homeostatic
physiological roles, are involved in innate immunity, and cause inflammation when in …

Background Alzheimer's disease is the most common dementia in the elderly, and the
potential of peripheral biochemical markers as complementary tools in the neuropsychiatric …

Disease progression in multiple sclerosis occurs within the interface of glial activation and
gliosis. This study aimed to investigate the relationship between biomarkers of different glial …

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Postmortem demonstration of increased expression of biologically active S100B in
Alzheimer's disease (AD) and its relation to progression of neuropathological changes …

In recent years, there has been an increased interest in the clinical use of brain markers. The
S100B is a calciumbinding peptide and is used as a parameter of glial activation and/or …

Abstract “Classic” neurodegenerative disorders, such as Alzheimer's disease and
amyotrophic lateral sclerosis share common pathophysiological features and involve …