'If you assume, you can make an ass out of u and me': a decade of the disector for stereological counting of particles in 3D space

TM Mayhew, HJ Gundersen - Journal of anatomy, 1996 - pmc.ncbi.nlm.nih.gov
The year 1984 was a watershed in stereology. It saw the introduction of highly efficient and
unbiased design-based methods for counting the number of arbitrary objects in 3 …

A review of recent advances in stereology for quantifying neural structure

TM Mayhew - Journal of neurocytology, 1992 - Springer
The science of stereology has undergone a revolution over the past decade with the
introduction of design-based (assumption-or model-free) methods which are highly efficient …

Estradiol mediates fluctuation in hippocampal synapse density during the estrous cycle in the adult rat [published erratum appears in J Neurosci 1992 Oct; 12 (10) …

CS Woolley, BS McEwen - Journal of Neuroscience, 1992 - jneurosci.org
We have found that the density of synapses in the stratum radiatum of the hippocampal CA1
region in the adult female rat is sensitive to estradiol manipulation and fluctuates naturally as …

Synapses are lost during aging in the primate prefrontal cortex

A Peters, C Sethares, JI Luebke - Neuroscience, 2008 - Elsevier
An electron microscopic analysis has been carried out on the effects of age on the numerical
density of both excitatory (asymmetric) and inhibitory (symmetric) synapses in the neuropil of …

Contributions of dendritic spines and perforated synapses to synaptic plasticity

RKS Calverley, DG Jones - Brain research reviews, 1990 - Elsevier
The dynamic nature of synaptic connections has presented morphologists with considerable
problems which, from a structural perspective, have frustrated the development of ideas on …

Aberrant restoration of spines and their synapses in L-DOPA-induced dyskinesia: involvement of corticostriatal but not thalamostriatal synapses

Y Zhang, GE Meredith, N Mendoza-Elias… - Journal of …, 2013 - jneurosci.org
We examined the structural plasticity of excitatory synapses from corticostriatal and
thalamostriatal pathways and their postsynaptic targets in adult Sprague-Dawley rats to …

Stereology: a method for analyzing images

JP Royet - Progress in neurobiology, 1991 - Elsevier
This review deals with notions of shape, sizes, numbers, densities and orientation in space,
all basic concepts in stereology. With the initiation by Delesse in 1847, but mainly since the …

Neuroprotection of ischemic brain by vascular endothelial growth factor is critically dependent on proper dosage and may be compromised by angiogenesis

PS Manoonkitiwongsa, RL Schultz… - Journal of Cerebral …, 2004 - journals.sagepub.com
Vascular endothelial growth factor (VEGF) is currently considered a potential pharmacologic
agent for stroke therapy because of its strong neuroprotective and angiogenic capacities …

Deficits of neuronal density in CA1 and synaptic density in the dentate gyrus, CA3 and CA1, in a mouse model of Down syndrome

MA Kurt, MI Kafa, M Dierssen, DC Davies - Brain research, 2004 - Elsevier
Ts65Dn mice are partially trisomic for the distal region of MMU16, which is homologous with
the obligate segment of HSA21 triplicated in Down syndrome (DS). Ts65Dn mice are …

The effects of aging on layer 1 in area 46 of prefrontal cortex in the rhesus monkey.

A Peters, C Sethares, MB Moss - Cerebral cortex (New York, NY …, 1998 - academic.oup.com
The effect of age on layer 1 of area 46 of prefrontal cortex was determined in the cerebral
cortices of 15 rhesus monkeys, 13 of which had been behaviorally tested. Five of the …