Traditional therapeutic approaches such as chemotherapy and radiation therapy have
burdened cancer patients with onerous physical and psychological challenges …

A cancer diagnosis is one of the most feared events. Rarely diagnosed before the late
twentieth century, cancer now competes with cardiovascular disease as the leading cause of …

In principle, proton therapy offers a substantial clinical advantage over conventional photon
therapy. This is because of the unique depth-dose characteristics of protons, which can be …

Radiotherapy with high-energy charged particles has become an attractive therapeutic
option for patients with several tumour types because this approach better spares healthy …

Charged particle therapy is generally regarded as cutting-edge technology in oncology.
Many proton therapy centres are active in the USA, Europe, and Asia, but only a few centres …

Importance Understanding the adverse effects of contemporary approaches to localized
prostate cancer treatment could inform shared decision making. Objective To compare …

Purpose SpaceOAR, a Food and Drug Administration–approved hydrogel intended to create
a rectal–prostate space, was evaluated in a single-blind phase III trial of image guided …

Charged particle therapy has been largely driven and influenced by nuclear physics. The
increase in energy deposition density along the ion path in the body allows reducing the …

Importance Patients diagnosed with localized prostate cancer have to decide among
treatment strategies that may differ in their likelihood of adverse effects. Objective To …

Approximately 50% of all patients with cancer receive radiation therapy at some point during
the course of their treatment, and the majority of these patients are treated with curative …