Recent progress on photodynamic therapy and photothermal therapy

H Kim, M Yang, N Kwon, M Cho, J Han… - Bulletin of the …, 2023 - Wiley Online Library
Noninvasive treatments for terminal cancer patients constitute a new trend in tumor
treatment. Therefore, phototherapy, including photodynamic therapy (PDT) and …

Fluorescent probes for the detection of chemical warfare agents

WQ Meng, AC Sedgwick, N Kwon, M Sun… - Chemical Society …, 2023 - pubs.rsc.org
Chemical warfare agents (CWAs) are toxic chemicals that have been intentionally
developed for targeted and deadly use on humans. Although intended for military targets …

A strategy of monitoring acetylcholinesterase and screening of natural inhibitors from Uncaria for Alzheimer's disease therapy based on near-infrared fluorescence …

H Wang, Z Yan, W Yang, R Liu, G Fan, Z Gu… - Sensors and Actuators B …, 2025 - Elsevier
Alzheimer's disease is a progressive neurodegenerative disorder characterized by memory
loss and cognitive decline. A key factor in its pathogenesis is the decreased level or …

A space‐dependent 'enzyme‐substrate'type probe based on 'carboxylesterase‐amide group'for ultrafast fluorescent imaging orthotopic hepatocellular carcinoma

Y Wen, N **g, M Zhang, F Huo, Z Li… - Advanced Science, 2023 - Wiley Online Library
Fast and selective fluorescence imaging for a biomarker to related‐disease diagnosis
remains a significant challenge due to complex physical environment. Human …

An Enzyme‐Activatable Aggregation‐Induced‐Emission Probe: Intraoperative Pathological Fluorescent Diagnosis of Pancreatic Cancer via Specific Cathepsin E

Z Zhu, Q Wang, X Chen, Q Wang, C Yan… - Advanced …, 2022 - Wiley Online Library
Pancreatic cancer (PC) is one of the most devastating malignant tumors. However,
fluorescence probes for early clinical diagnosis of PC often encounter difficulties in accuracy …

Near-infrared-excitable acetylcholinesterase-activated fluorescent probe for sensitive and anti-interference detection of pesticides in colored food

Z Wu, Z Hao, Y Chai, A Li, C Wang, X Zhang… - Biosensors and …, 2023 - Elsevier
The development of a common and anti-interference acetylcholinesterase (AChE) inhibition
assay for plant-originated food samples has been of great challenge because of the …

Optical imaging probes for selective detection of butyrylcholinesterase

M Dirak, J Chan, S Kolemen - Journal of Materials Chemistry B, 2024 - pubs.rsc.org
Butyrylcholinesterase (BChE), a member of the human serine hydrolase family, is an
essential enzyme for cholinergic neurotransmission as it catalyzes the hydrolysis of …

Practical Three-Component Regioselective Synthesis of Drug-Like 3-Aryl(or heteroaryl)-5,6-dihydrobenzo[h]cinnolines as Potential Non-Covalent Multi-Targeting …

H Mousavi, M Rimaz, B Zeynizadeh - ACS Chemical …, 2024 - ACS Publications
Neurodegenerative diseases (NDs) are one of the prominent health challenges facing
contemporary society, and many efforts have been made to overcome and (or) control it. In …

Recent advances in ratiometric fluorescence imaging of enzyme activity in vivo

ED Cosco, M Bogyo - Current Opinion in Chemical Biology, 2024 - Elsevier
Among molecular imaging modalities that can monitor enzyme activity in vivo, optical
imaging provides sensitive, molecular-level information at low-cost using safe and non …

A responsive AIE-active fluorescent probe for visualization of acetylcholinesterase activity in vitro and in vivo

C **ang, M Dirak, Y Luo, Y Peng, L Cai… - Materials Chemistry …, 2022 - pubs.rsc.org
Acetylcholinesterase (AChE) is a significant enzyme, which plays critical roles in numerous
physiological and pathological processes. Thus, selective, and sensitive real-time imaging …