Background: Cancer has been considered to be a global health concern due to the impact of
disease on the quality of life. The continual increase of cancer cases as well as the …

Microwave-assisted (MWA) multicomponent reactions (MCRs) have successfully emerged
as one of the useful tools in the synthesis of biologically relevant heterocycles. These …

Here we develop a novel visible-light-driven three-component cyclization by trap** an 1, 3-
vinylimine ion intermediate for the direct synthesis of pyrimido [1, 2-b] indazole derivatives …

Novel xanthine and imidazolone derivatives were synthesized based on oxazolone
derivatives 2a-c as a key intermediate. The corresponding xanthine 3-5 and imidazolone …

The objective of this review is to list the structures composed of a pyridopyrimidine moiety
which have shown a therapeutic interest or have already been approved for use as …

Due to their extensive applications in pharmaceuticals and natural substances, organic
synthesis and heterocyclic compounds have been at the forefront of research for many …

Background: Recently, pyrido [2, 3-d] pyrimidine, triazolopyrimidine, thiazolopyrimidine,
quinoline, and pyrazole derivatives have gained attention due to their diverse biological …

Antioxidants have a significant contribution in the cell protection against free radicals which
may induce oxidative stress, and permanently damage the cells causing different disorders …

The rationale behind drug design is the strategic utilization of heterocyclic fragments with
specific physicochemical properties to form molecular targeted agents. Among the …

The present method provides a wide scope and quick access to dihydropyrido [2, 3-d: 6, 5-
d′] dipyrimidinetetraone and pyrimido [4, 5-d] pyrimidine derivatives in good to excellent …