Production and biological function of volatile esters in Saccharomyces cerevisiae

SMG Saerens, FR Delvaux, KJ Verstrepen… - Microbial …, 2010 - Wiley Online Library
The need to understand and control ester synthesis is driven by the fact that esters play a
key role in the sensorial quality of fermented alcoholic beverages like beer, wine and sake …

Adaptive Response and Tolerance to Weak Acids in Saccharomyces cerevisiae: A Genome-Wide View

NP Mira, MC Teixeira, I Sá-Correia - Omics: a journal of integrative …, 2010 - liebertpub.com
Weak acids are widely used as food preservatives (eg, acetic, propionic, benzoic, and sorbic
acids), herbicides (eg, 2, 4-dichlorophenoxyacetic acid), and as antimalarial (eg, artesunic …

Fungicide-Driven Evolution and Molecular Basis of Multidrug Resistance in Field Populations of the Grey Mould Fungus Botrytis cinerea

M Kretschmer, M Leroch, A Mosbach, AS Walker… - PLoS …, 2009 - journals.plos.org
The grey mould fungus Botrytis cinerea causes losses of commercially important fruits,
vegetables and ornamentals worldwide. Fungicide treatments are effective for disease …

Antifungal drug resistance mechanisms in fungal pathogens from the perspective of transcriptional gene regulation

D Sanglard, A Coste, S Ferrari - FEMS yeast research, 2009 - academic.oup.com
Fungi are primitive eukaryotes and have adapted to a variety of niches during evolution.
Some fungal species may interact with other life forms (plants, insects, mammals), but are …

Multidimensional engineering of Saccharomyces cerevisiae for efficient synthesis of medium-chain fatty acids

Z Zhu, Y Hu, PG Teixeira, R Pereira, Y Chen… - Nature Catalysis, 2020 - nature.com
Medium-chain fatty acids (MCFAs; C6–C12) are valuable molecules used for biofuel and
oleochemical production; however, it is challenging to synthesize these fatty acids efficiently …

Membrane transporter engineering in industrial biotechnology and whole cell biocatalysis

DB Kell, N Swainston, P Pir, SG Oliver - Trends in biotechnology, 2015 - cell.com
Because they mainly do not involve chemical changes, membrane transporters have been a
Cinderella subject in the biotechnology of small molecule production, but this is a serious …

Genome sequence of Valsa canker pathogens uncovers a potential adaptation of colonization of woody bark

Z Yin, H Liu, Z Li, X Ke, D Dou, X Gao, N Song… - New …, 2015 - Wiley Online Library
Canker caused by ascomycetous Valsa species are among the most destructive diseases of
woody plants worldwide. These pathogens are distinct from other pathogens because they …

Targeting efflux pumps to overcome antifungal drug resistance

AR Holmes, TS Cardno, JJ Strouse… - Future Medicinal …, 2016 - Taylor & Francis
Resistance to antifungal drugs is an increasingly significant clinical problem. The most
common antifungal resistance encountered is efflux pump-mediated resistance of Candida …

How drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusion

DB Kell, SG Oliver - Frontiers in pharmacology, 2014 - frontiersin.org
One approach to experimental science involves creating hypotheses, then testing them by
varying one or more independent variables, and assessing the effects of this variation on the …

Adaptive laboratory evolution of tolerance to dicarboxylic acids in Saccharomyces cerevisiae

R Pereira, Y Wei, E Mohamed, M Radi, C Malina… - Metabolic …, 2019 - Elsevier
Improving the growth phenotypes of microbes in high product concentrations is an essential
design objective in the development of robust cell factories. However, the limited knowledge …