The multi-domain non-structural protein 3 (Nsp3) is the largest protein encoded by the
coronavirus (CoV) genome, with an average molecular mass of about 200 kD. Nsp3 is an …

Hepatitis E virus (HEV) infection can lead to acute and chronic hepatitis as well as to
extrahepatic manifestations such as neurological and renal disease; it is the most common …

At least 20 million hepatitis E virus (HEV) infections occur annually, with> 3 million
symptomatic cases and∼ 60,000 fatalities. Hepatitis E is generally self-limiting, with a case …

Poly-adenosine diphosphate-ribose polymerases (PARPs) promote ADP-ribosylation, a
highly conserved, fundamental posttranslational modification (PTM). PARP catalytic …

Hepatitis E virus (HEV) infection is a worldwide disease. An improved understanding of the
natural history of HEV infection has been achieved within the last decade. Several reservoirs …

The family Hepeviridae includes enterically transmitted small non-enveloped positive-sense
RNA viruses. It includes the genera Piscihepevirus, whose members infect fish, and …

Hepatitis E virus (HEV) is a major cause of viral hepatitis globally. Zoonotic HEV is an
important cause of chronic hepatitis in immunocompromised patients. The rapid …

This review focuses on the monophyletic group of animal RNA viruses united in the order
Nidovirales. The order includes the distantly related coronaviruses, toroviruses, and …

Hepatitis E virus (HEV) was discovered during the Soviet occupation of Afghanistan in the
1980s, after an outbreak of unexplained hepatitis at a military camp. A pooled faecal extract …

Our previous studies demonstrated that membrane-associated hepatitis E virus (HEV)
particles—now considered “quasi-enveloped particles”—are present in the multivesicular …