Clinical Implications of the Molecular and Genomic Landscape of Upper Tract Urothelial Carcinoma

S Jaime-Casas, A Tripathi, SK Pal, W Yip - Current Urology Reports, 2025 - Springer
Abstract Purpose of Review Upper tract urothelial carcinoma (UTUC) is an aggressive entity
with treatment strategies mirroring bladder cancer. Genomic and molecular profiling allows …

From Detection to Cure–Emerging Roles for Urinary Tumor DNA (utDNA) in Bladder Cancer

JA Linscott, H Miyagi, PB Murthy, S Yao… - Current Oncology …, 2024 - Springer
Summary utDNA shows promise for improving all phases of bladder cancer care, paving the
way for personalized treatment strategies. Building from current research, future …

Advancements in Urothelial Cancer Care: Optimizing Treatment for Your Patient

G Hemenway, JF Anker, P Riviere, BS Rose… - American Society of …, 2024 - ascopubs.org
The standard treatment paradigm for muscle invasive bladder cancer has been neoadjuvant
cisplatin-based chemotherapy followed by radical cystectomy. However, efforts are ongoing …

[HTML][HTML] Circulating Tumor DNA: A New Research Frontier in Urological Oncology from Localized to Metastatic Disease

M Garofoli, BA Maiorano, G Bruno, G Giordano… - European Urology …, 2024 - Elsevier
Background and objective Circulating tumor DNA (ctDNA) testing provides valuable
prognostic and predictive information for guiding therapeutic choices and monitoring …

Longitudinal glioma monitoring via cerebrospinal fluid cell-free DNA: one patient at a time

C Riviere-Cazaux, X Dong, W Mo, C Dai, LP Carlstrom… - medRxiv, 2024 - medrxiv.org
ABSTRACT IMPORTANCE Current methods for glioma treatment response assessment are
limited. Intracranial cerebrospinal fluid (CSF) may provide a previously untapped source of …

Plasma-Derived Cell-Free DNA as a Biomarker for Early Detection, Prognostication, and Personalized Treatment of Urothelial Carcinoma

S Bhalla, R Passarelli, A Biswas, S De… - Journal of Clinical …, 2024 - mdpi.com
Bladder cancer (BC) is one of the most common malignancies in the United States, with over
80,000 new cases and 16,000 deaths each year. Urothelial carcinoma (UC) is the most …

Gold standard nephroureterectomy, chemoprophylaxis and surveillance in upper tract urothelial carcinoma

G Basile, M Bandini, R Li, MA Poch… - Current Opinion in …, 2025 - journals.lww.com
Minimally invasive surgery has been associated with comparable oncological outcomes to
the open approach while improving postoperative morbidity. In these cases, bladder cuff …

Longitudinal tumor-informed circulating tumor DNA status predicts disease upstaging and poor prognosis for patients undergoing radical cystectomy

R Ben-David, N Tillu, S Cumarasamy… - European Urology …, 2024 - Elsevier
Background and objective Decision-making on the use of neoadjuvant and adjuvant
treatment for patients with bladder cancer undergoing radical cystectomy (RC) currently …

Blood-based liquid biopsy: A promising noninvasive test in diagnosis, surveillance, and prognosis of patients with upper tract urothelial carcinoma

A Ghoreifi, SN Shishido, S Sayeed… - … Oncology: Seminars and …, 2024 - Elsevier
Objectives To assess the efficacy of blood-based liquid biopsy in the diagnosis, surveillance,
and prognosis of upper tract urothelial carcinoma (UTUC). Methods and Materials In this …

Reply to Jue et al. Overcoming Understaging and Undergrading in Upper Tract Urothelial Carcinoma. Comment on “Ghoreifi et al. Modern Kidney-Sparing …

A Ghoreifi, R Sari Motlagh, G Fuchs - Cancers, 2024 - mdpi.com
Background: Open Access Reply Reply to Jue et al. Overcoming Understaging and
Undergrading in Upper Tract Urothelial Carcinoma. Comment on “Ghoreifi et al. Modern …