Pathophysiology of sepsis-induced myocardial dysfunction
X Lv, H Wang - Military Medical Research, 2016 - Springer
Sepsis-induced myocardial dysfunction is a common complication in septic patients and is
associated with increased mortality. In the clinical setting, it was once believed that …
associated with increased mortality. In the clinical setting, it was once believed that …
New insights into the role of ferroptosis in cardiovascular diseases
Cardiovascular diseases (CVDs) are the principal cause of disease burden and death
worldwide. Ferroptosis is a new form of regulated cell death mainly characterized by altered …
worldwide. Ferroptosis is a new form of regulated cell death mainly characterized by altered …
[HTML][HTML] STING-IRF3 contributes to lipopolysaccharide-induced cardiac dysfunction, inflammation, apoptosis and pyroptosis by activating NLRP3
N Li, H Zhou, H Wu, Q Wu, M Duan, W Deng, Q Tang - Redox biology, 2019 - Elsevier
Mountainous evidence suggests that inflammation, cardiomyocyte apoptosis and pyroptosis
are involved in the development of sepsis and sepsis-induced cardiomyopathy (SIC) …
are involved in the development of sepsis and sepsis-induced cardiomyopathy (SIC) …
[HTML][HTML] Melanin nanoparticles alleviate sepsis-induced myocardial injury by suppressing ferroptosis and inflammation
C Liu, Q Zou, H Tang, J Liu, S Zhang, C Fan, J Zhang… - Bioactive materials, 2023 - Elsevier
Myocardial injury as one of the severe complications leads to the increasing morbidity and
mortality in patients with sepsis. Recent studies reported that reactive oxygen species (ROS) …
mortality in patients with sepsis. Recent studies reported that reactive oxygen species (ROS) …
Berberine alleviates doxorubicin-induced myocardial injury and fibrosis by eliminating oxidative stress and mitochondrial damage via promoting nrf-2 pathway …
Y Wang, J Liao, Y Luo, M Li, X Su, B Yu, J Teng… - International journal of …, 2023 - mdpi.com
Doxorubicin (DOX)-related cardiotoxicity has been recognized as a serious complication of
cancer chemotherapy. Effective targeted strategies for myocardial protection in addition to …
cancer chemotherapy. Effective targeted strategies for myocardial protection in addition to …
Corilagin alleviates LPS-induced sepsis through inhibiting pyroptosis via targeting TIR domain of MyD88 and binding CARD of ASC in macrophages
S Wu, J Liao, G Hu, L Yan, X Su, J Ye, C Zhang… - Biochemical …, 2023 - Elsevier
Sepsis is a dysregulated systemic inflammatory response caused by infection that leads to
multiple organ injury and high mortality without effective treatment. Corilagin, a natural …
multiple organ injury and high mortality without effective treatment. Corilagin, a natural …
[HTML][HTML] Gas6 attenuates lipopolysaccharide‑induced TNF‑α expression and apoptosis in H9C2 cells through NF‑κB and MAPK inhibition via the Axl/PI3K/Akt pathway
M Li, J Ye, G Zhao, G Hong, X Hu… - International …, 2019 - spandidos-publications.com
Therapeutic agents used to treat sepsis‑induced cardiac dysfunction are designed to
suppress tumor necrosis factor (TNF)‑α release and inhibit cell apoptosis. Exogenous …
suppress tumor necrosis factor (TNF)‑α release and inhibit cell apoptosis. Exogenous …
Hsp22 ameliorates lipopolysaccharide-induced myocardial injury by inhibiting inflammation, oxidative stress, and apoptosis
Y Yu, LL Hu, L Liu, LL Yu, JP Li, J Rao, LJ Zhu… - …, 2021 - Taylor & Francis
Sepsis-induced myocardial dysfunction (SIMD) is ubiquitous in septic shock patients and is
associated with high morbidity and mortality rates. Heat shock protein 22 (Hsp22), which …
associated with high morbidity and mortality rates. Heat shock protein 22 (Hsp22), which …
Alamandine attenuates sepsis-associated cardiac dysfunction via inhibiting MAPKs signaling pathways
P Li, XR Chen, F Xu, C Liu, C Li, H Liu, H Wang, W Sun… - Life Sciences, 2018 - Elsevier
Sepsis-induced myocardial dysfunction represents a major cause of death. Alamandine is
an important biologically active peptide. The present study evaluated whether alamandine …
an important biologically active peptide. The present study evaluated whether alamandine …
Catecholamine induces Kupffer cell apoptosis via growth differentiation factor 15 in alcohol-associated liver disease
Chronic alcohol consumption often induces hepatic steatosis but rarely causes severe
inflammation in Kupffer cells (KCs) despite the increased hepatic influx of …
inflammation in Kupffer cells (KCs) despite the increased hepatic influx of …