A review: Small organic molecule dual/multi-organelle-targeted fluorescent probes

Y Huang, J Liang, Z Fan - Talanta, 2023 - Elsevier
In recent years, the dual/multi-organelle-targeted fluorescent probe based on small organic
molecules has good biocompatibility and can visualize the interaction between different …

Vesicle trafficking and vesicle fusion: mechanisms, biological functions, and their implications for potential disease therapy

L Cui, H Li, Y **, Q Hu, H Liu, J Fan, Y **ang… - Molecular …, 2022 - Springer
Intracellular vesicle trafficking is the fundamental process to maintain the homeostasis of
membrane-enclosed organelles in eukaryotic cells. These organelles transport cargo from …

Graphene oxide nanosheets induce mitochondrial fragmentation by cutting through membrane

X Shao, Z Fang, M Li, W Zou, Q Wang… - ACS Materials …, 2023 - ACS Publications
Graphene oxide (GO)-based nanomaterials have unique physical, chemical, and biological
properties that make their use in biomedical research and nanomedicine of enormous …

Fluorescent probes design strategies for imaging mitochondria and lysosomes

H Chen, Z Yu, S Ren, Y Qiu - Frontiers in Pharmacology, 2022 - frontiersin.org
Modern cellular biology faces several major obstacles, such as the determination of the
concentration of active sites corresponding to chemical substances. In recent years, the …

Tailoring the pKa of Fluorescence Lifetime Imaging Probes to Visualize Aggrephagy and Resolve Its Microenvironmental Viscosity

Y Wei, X Gao, J Fang, Y **ao, J Liu, Y Liu… - Analytical …, 2024 - ACS Publications
Aggrephagy describes lysosomal transport and degradation of protein aggregates via
cellular macroautophagy, a key mechanism to prevent neurodegenerative diseases. Here …

Super‐resolution analyzing spatial organization of lysosomes with an organic fluorescent probe

L Wang, R Chen, G Han, X Liu, T Huang, J Diao… - …, 2022 - Wiley Online Library
Lysosomes are multifunctional organelles involved in macromolecule degradation, nutrient
sensing, and autophagy. Live imaging has revealed lysosome subpopulations with …

The function of VAMP2 in mediating membrane fusion: An overview

C Yan, J Jiang, Y Yang, X Geng… - Frontiers in Molecular …, 2022 - frontiersin.org
Vesicle-associated membrane protein 2 (VAMP2, also known as synaptobrevin-2), encoded
by VAMP2 in humans, is a key component of the soluble N-ethylmaleimide-sensitive factor …

Constant conversion rate of endolysosomes revealed by a pH-sensitive fluorescent probe

R Chen, L Wang, G Ding, G Han, K Qiu, Y Sun… - ACS …, 2023 - ACS Publications
Endolysosome dynamics plays an important role in autophagosome biogenesis. Hence,
imaging the subcellular dynamics of endolysosomes using high-resolution fluorescent …

Super-resolution fluorescence microscopic imaging in pathogenesis and drug treatment of neurological disease

J Gong, Z **, H Chen, J He, Y Zhang… - Advanced Drug Delivery …, 2023 - Elsevier
Since super-resolution fluorescence microscopic technology breaks the diffraction limit that
has existed for a long time in optical imaging, it can observe the process of synapses formed …

[HTML][HTML] Mitochondrial nucleoid condensates drive peripheral fission through high membrane curvature

Q Chen, LY Liu, Z Tian, Z Fang, KN Wang, X Shao… - Cell Reports, 2023 - cell.com
Mitochondria are dynamic organelles that undergo fusion and fission events, in which the
mitochondrial membrane and DNA (mtDNA) play critical roles. The spatiotemporal …