A community-based transcriptomics classification and nomenclature of neocortical cell types

R Yuste, M Hawrylycz, N Aalling, A Aguilar-Valles… - Nature …, 2020 - nature.com
To understand the function of cortical circuits, it is necessary to catalog their cellular
diversity. Past attempts to do so using anatomical, physiological or molecular features of …

Design and fabrication of organ-on-chips: promises and challenges

A Tajeddin, N Mustafaoglu - Micromachines, 2021 - mdpi.com
The advent of the miniaturization approach has influenced the research trends in almost all
disciplines. Bioengineering is one of the fields benefiting from the new possibilities of …

A guide to the BRAIN Initiative Cell Census Network data ecosystem

M Hawrylycz, ME Martone, GA Ascoli, JG Bjaalie… - PLoS …, 2023 - journals.plos.org
Characterizing cellular diversity at different levels of biological organization and across data
modalities is a prerequisite to understanding the function of cell types in the brain …

Common cell type nomenclature for the mammalian brain

JA Miller, NW Gouwens, B Tasic, F Collman… - Elife, 2020 - elifesciences.org
The advancement of single-cell RNA-sequencing technologies has led to an explosion of
cell type definitions across multiple organs and organisms. While standards for data and …

Hippocampome. org 2.0 is a knowledge base enabling data-driven spiking neural network simulations of rodent hippocampal circuits

DW Wheeler, JD Kopsick, N Sutton, C Tecuatl… - Elife, 2024 - elifesciences.org
Hippocampome. org is a mature open-access knowledge base of the rodent hippocampal
formation focusing on neuron types and their properties. Previously, Hippocampome. org v1 …

Assisted neuroscience knowledge extraction via machine learning applied to neural reconstruction metadata on NeuroMorpho. Org

K Bijari, Y Zoubi, GA Ascoli - Brain Informatics, 2022 - Springer
The amount of unstructured text produced daily in scholarly journals is enormous.
Systematically identifying, sorting, and structuring information from such a volume of data is …

A multimodal cell census and atlas of the mammalian primary motor cortex

BRAIN Initiative Cell Census Network (BICCN)… - Biorxiv, 2020 - biorxiv.org
We report the generation of a multimodal cell census and atlas of the mammalian primary
motor cortex (MOp or M1) as the initial product of the BRAIN Initiative Cell Census Network …

Circuit analysis of the Drosophila brain using connectivity-based neuronal classification reveals organization of key communication pathways

K Mehta, RF Goldin, GA Ascoli - Network Neuroscience, 2023 - direct.mit.edu
We present a functionally relevant, quantitative characterization of the neural circuitry of
Drosophila melanogaster at the mesoscopic level of neuron types as classified exclusively …

An open-source framework for neuroscience metadata management applied to digital reconstructions of neuronal morphology

K Bijari, MA Akram, GA Ascoli - Brain Informatics, 2020 - Springer
Research advancements in neuroscience entail the production of a substantial amount of
data requiring interpretation, analysis, and integration. The complexity and diversity of …

The past, present and future of neuroscience data sharing: a perspective on the state of practices and infrastructure for FAIR

ME Martone - Frontiers in Neuroinformatics, 2024 - frontiersin.org
Neuroscience has made significant strides over the past decade in moving from a largely
closed science characterized by anemic data sharing, to a largely open science where the …