Advances in ultra-high-resolution mass spectrometry for pharmaceutical analysis

E Deschamps, V Calabrese, I Schmitz, M Hubert-Roux… - Molecules, 2023 - mdpi.com
Pharmaceutical analysis refers to an area of analytical chemistry that deals with active
compounds either by themselves (drug substance) or when formulated with excipients (drug …

Parallelized acquisition of orbitrap and astral analyzers enables high-throughput quantitative analysis

HI Stewart, D Grinfeld, A Giannakopulos… - Analytical …, 2023 - ACS Publications
The growing trend toward high-throughput proteomics demands rapid liquid
chromatography–mass spectrometry (LC–MS) cycles that limit the available time to gather …

Recent developments in clinical plasma proteomics—applied to cardiovascular research

NB Palstrøm, R Matthiesen, LM Rasmussen, HC Beck - Biomedicines, 2022 - mdpi.com
The human plasma proteome mirrors the physiological state of the cardiovascular system, a
fact that has been used to analyze plasma biomarkers in routine analysis for the diagnosis …

Optimization of mass spectrometric parameters in data dependent acquisition for untargeted metabolomics on the basis of putative assignments

HA Assress, MG Ferruzzi, RS Lan - Journal of the American …, 2023 - ACS Publications
Optimization of mass spectrometric parameters for a data dependent acquisition (DDA)
experiment is essential to increase the MS/MS coverage and hence increase metabolite …

From Hydrocarbons to Highly Functionalized Molecules in a Single Measurement: Comprehensive Analysis of Complex Gas Mixtures by Multi-Pressure Chemical …

A Shcherbinin, H Finkenzeller, J Mikkilä… - Analytical …, 2024 - ACS Publications
Chemical Ionization Mass Spectrometry (CIMS) is a well-established analytical method in
atmospheric research, process monitoring, forensics, breathomics, and food science …

Selected ion monitoring for orbitrap-based metabolomics

W Lu, MJ McBride, WD Lee, X ** in peripheral blood of single multiple myeloma patients
X Ye, Y Yang, J Zhou, L Xu, L Wu, P Huang, C Feng… - Analytica Chimica …, 2021 - Elsevier
T cells play crucial roles in our immunity against hematological tumors by inducing
sustained immune responses. Flow cytometry-based detection of a limited number of …

[PDF][PDF] Selected Ion Monitoring for Orbitrap-Based Metabolomics. Metabolites 2024, 14, 184

W Lu, MJ McBride, WD Lee, X **ng, X Xu, X Li… - 2024 - researchgate.net
Orbitrap mass spectrometry in full scan mode enables the simultaneous detection of
hundreds of metabolites and their isotope-labeled forms. Yet, sensitivity remains limiting for …

[BOOK][B] Method Development and Applications of Low-Input Proteomics

Y Yang - 2021 - search.proquest.com
Proteomics offers complementary and more direct information to genomics and
transcriptomics, essential for the understanding of complex biological processes. Low-input …