During oncogenesis, cancer not only escapes the body's regulatory mechanisms, but also
gains the ability to affect local and systemic homeostasis. Specifically, tumors produce …

Melanin is a biological pigment formed by indoles and phenolic compounds. It is widely
found in living organisms and has a variety of unique properties. Due to its diverse …

Ultraviolet radiation (UVR) is primarily recognized for its detrimental effects such as
cancerogenesis, skin aging, eye damage, and autoimmune disorders. With exception of …

The skin, including the hypodermis, is the largest body organ and is in constant contact with
the environment. Neurogenic inflammation is the result of the activity of nerve endings and …

Novel pathways of vitamin D3, lumisterol 3 (L3), and tachysterol 3 (T3) activation have been
discovered, initiated by CYP11A1 and/or CYP27A1 in the case of L3 and T3. The resulting …

With the advancement of living standards in modern society and the emergence of an aging
population, an increasing number of people are becoming interested in the topic of aging …

The increase in air pollution worldwide represents an environmental risk factor that has
global implications for the health of humans worldwide. The skin of billions of people is …

Simple Summary Despite recent advances in diagnosis and therapy, malignant melanoma
poses a significant problem both to clinicians and cancer researchers due to its resistance to …

Air pollutants deteriorate the survival environment and endanger human health around the
world. A large number of studies have confirmed that air pollution jeopardizes multiple …

Skin aging is a complex process involving structural and functional changes and is
characterized by a decrease in collagen content, reduced skin thickness, dryness, and the …