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[HTML][HTML] Mechanistic role of HPV-associated early proteins in cervical cancer: Molecular pathways and targeted therapeutic strategies
Purpose Cervical cancer (CC), one of the major causes of death of women throughout the
world is primarily caused due to Human Papilloma Virus (HPV) 16 and 18. The early region …
world is primarily caused due to Human Papilloma Virus (HPV) 16 and 18. The early region …
Role of the tumor microenvironment in the lymphatic metastasis of cervical cancer
L Wang, S Yi, Y Teng, W Li… - Experimental and …, 2023 - spandidos-publications.com
Lymphatic metastasis is the primary type of cervical cancer metastasis and is associated
with an extremely poor prognosis in patients. The tumor microenvironment primarily includes …
with an extremely poor prognosis in patients. The tumor microenvironment primarily includes …
Antitumor effect of chalcone derivatives against human prostate (LNCaP and PC-3), cervix HPV-positive (HeLa) and lymphocyte (Jurkat) cell lines and their effect on …
Chalcones are synthetic and naturally occurring compounds that have been widely
investigated as anticancer agents. In this work, the effect of chalcones 1–18 against the …
investigated as anticancer agents. In this work, the effect of chalcones 1–18 against the …
Tumor-and host-derived heparanase-2 (Hpa2) attenuates tumorigenicity: role of Hpa2 in macrophage polarization and BRD7 nuclear localization
Little attention was given to heparanase 2 (Hpa2) over the last two decades, possibly
because it lacks a heparan sulfate (HS)-degrading activity typical of heparanase. Emerging …
because it lacks a heparan sulfate (HS)-degrading activity typical of heparanase. Emerging …
Sequencing-based transcriptome analysis reveals diversification of immune response-and angiogenesis-related expression patterns of early-stage cervical carcinoma …
Background Molecular diversity of virus-associated cervical cancer remains a relatively
underexplored issue, and interrelations of immunologic and angiogenic features during the …
underexplored issue, and interrelations of immunologic and angiogenic features during the …
A prognostic model for cervical cancer based on ferroptosis-related genes
H Du, Y Tang, X Ren, F Zhang, W Yang… - Frontiers in …, 2022 - frontiersin.org
Background Ferroptosis is widely involved in the occurrence and development of various
cancers, but a specific mechanism involving ferroptosis in cervical cancer is still unclear …
cancers, but a specific mechanism involving ferroptosis in cervical cancer is still unclear …
Fibroblast stromal support model for predicting human papillomavirus-associated cancer drug responses
CD James, RL Lewis, AL Fakunmoju, AJ Witt… - Journal of …, 2024 - journals.asm.org
Currently, there are no specific antiviral therapeutic approaches targeting Human
papillomaviruses (HPVs), which cause around 5% of all human cancers. Specific antiviral …
papillomaviruses (HPVs), which cause around 5% of all human cancers. Specific antiviral …
Gynecological cancer tumor Microenvironment: Unveiling cellular complexity and therapeutic potential
Gynecological cancers, including ovarian, cervical, endometrial, and vulvar cancers, present
significant challenges in diagnosis and treatment globally. The tumor microenvironment …
significant challenges in diagnosis and treatment globally. The tumor microenvironment …
GuiErBai: a potent inhibitor, exhibiting broadly antitumor effect against cervical cancer in vitro and in vivo
H Qin, L Peng, Y Xu, Z Zhang, R Tian, Z Wan… - Frontiers in …, 2024 - frontiersin.org
Introduction: Cervical cancer (CC) ranks as the fourth most prevalent malignant tumor
among women worldwide, and is the fourth leading cause of cancer-related mortality …
among women worldwide, and is the fourth leading cause of cancer-related mortality …
Multi-omics analysis in tumor microenvironment and tumor heterogeneity
integrate multi-omics resources and has been successfully implemented in the analyzing of
various cancer types (4, 5). Multi-omics approaches also leave researchers with significant …
various cancer types (4, 5). Multi-omics approaches also leave researchers with significant …