Owing to advances in radiotherapy, the physical properties of radiation can be optimized to
enable individualized treatment; however, optimization is rarely based on biological …

Radiogenomics, focusing on the relationship between genomics and imaging phenotypes,
has been widely applied to address tumour heterogeneity and predict immune …

Ionizing radiation interacts with the immune system in many ways with a multiplicity that
mirrors the complexity of the immune system itself: namely the need to maintain a delicate …

Simple Summary Radiotherapy with carbon ions has been used for over 20 years in Asia
and Europe and is now planned in the USA. The physics advantages of carbon ions …

Human spaceflight is entering a new era of sustainable human space exploration. By 2030
humans will regularly fly to the Moon's orbit, return to the Moon's surface and preparations …

The advent of affordable and rapid next-generation DNA sequencing technology, along with
the US Supreme Court ruling invalidating gene patents, has led to a deluge of germline and …

Peptide receptor radionuclide therapy (PRRT) is a type of radiotherapy that targets peptide
receptors and is typically used for neuroendocrine tumours (NETs). Some of the key …

Background Epidemiological studies have indicated that exposure of the heart to doses of
ionizing radiation as low as 0.5 Gy increases the risk of cardiac morbidity and mortality with …

Hypofractionated radical radiotherapy is now an accepted standard of care for tumour sites
such as prostate and breast cancer. Much research effort is being directed towards more …

Tissue reactions and stochastic effects after exposure to ionising radiation are variable
between individuals but the factors and mechanisms governing individual responses are not …