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[HTML][HTML] Flavonoids: Their putative neurologic roles, epigenetic changes, and gut microbiota alterations in Parkinson's disease
Y Açar, D Ağagündüz, P De Cicco… - Biomedicine & …, 2023 - Elsevier
Abstract Parkinson's Disease (PD), a neurodegenerative disorder, is characterized by the
degeneration of progressive dopaminergic (DA) neurons in the substantia nigra region of …
degeneration of progressive dopaminergic (DA) neurons in the substantia nigra region of …
Understanding role of pesticides in development of Parkinson's disease: insights from Drosophila and rodent models
S Afsheen, AS Rehman, A Jamal, N Khan… - Ageing research …, 2024 - Elsevier
Parkinson's disease is a neurodegenerative illness linked to ageing, marked by the gradual
decline of dopaminergic neurons in the midbrain. The exact aetiology of Parkinson's disease …
decline of dopaminergic neurons in the midbrain. The exact aetiology of Parkinson's disease …
Epigenome-wide association study of peripheral immune cell populations in Parkinson's disease
MS Andersen, IS Leikfoss, IS Brorson… - NPJ Parkinson's …, 2023 - nature.com
Understanding the contribution of immune mechanisms to Parkinson's disease
pathogenesis is an important challenge, potentially of major therapeutic implications. To …
pathogenesis is an important challenge, potentially of major therapeutic implications. To …
Developmental origins of Parkinson's disease risk: perinatal exposure to the organochlorine pesticide dieldrin leads to sex-specific DNA modifications in critical …
J Kochmanski, M Virani, NC Kuhn, SL Boyd… - Toxicological …, 2024 - academic.oup.com
Epidemiological studies show that exposure to the organochlorine pesticide dieldrin is
associated with an increased risk of Parkinson's disease (PD). Animal studies support a link …
associated with an increased risk of Parkinson's disease (PD). Animal studies support a link …
[HTML][HTML] Calcium deregulation in neurodegeneration and neuroinflammation in Parkinson's Disease: Role of calcium-storing organelles and sodium–calcium …
G Bastioli, S Piccirillo, L Graciotti, M Carone, G Sprega… - Cells, 2024 - mdpi.com
Parkinson's disease (PD) is a progressive neurodegenerative disorder that lacks effective
treatment strategies to halt or delay its progression. The homeostasis of Ca2+ ions is crucial …
treatment strategies to halt or delay its progression. The homeostasis of Ca2+ ions is crucial …
Pain-free alpha-synuclein detection by low-cost hierarchical nanowire based electrode
GM Di Mari, M Scuderi, G Lanza, MG Salluzzo… - Nanomaterials, 2024 - mdpi.com
Analytical methods for the early detection of the neurodegenerative biomarker for
Parkinson's disease (PD), α-synuclein, are time-consuming and invasive, and require skilled …
Parkinson's disease (PD), α-synuclein, are time-consuming and invasive, and require skilled …
Converging peripheral blood microRNA profiles in Parkinson's disease and progressive supranuclear palsy
L Pavelka, A Rauschenberger, A Hemedan… - Brain …, 2024 - academic.oup.com
MicroRNAs act via targeted suppression of messenger RNA translation in the DNA–RNA–
protein axis. The dysregulation of microRNA (s) reflects the epigenetic changes affecting the …
protein axis. The dysregulation of microRNA (s) reflects the epigenetic changes affecting the …
Insights into Calpain activation and rho-ROCK signaling in Parkinson's disease and aging
A Gathings, V Zaman, NL Banik, A Haque - Biomedicines, 2024 - mdpi.com
Parkinson's disease (PD), a progressive neurodegenerative disease, has no cure, and
current therapies are not effective at halting disease progression. The disease affects mid …
current therapies are not effective at halting disease progression. The disease affects mid …
Metabolomic changes in rat serum after chronic exposure to glyphosate-based herbicide
O Daramola, CD Gutierrez Reyes, J Chávez-Reyes… - Metabolites, 2024 - mdpi.com
Glyphosate-based herbicides (GBHs) have gained extensive popularity in recent decades.
For many years, glyphosate has been regarded as harmless or minimally toxic to mammals …
For many years, glyphosate has been regarded as harmless or minimally toxic to mammals …
[HTML][HTML] Epigenetic Explorations of Neurological Disorders, the Identification Methods, and Therapeutic Avenues
Z Firdaus, X Li - International journal of molecular sciences, 2024 - mdpi.com
Neurodegenerative disorders are major health concerns globally, especially in aging
societies. The exploration of brain epigenomes, which consist of multiple forms of DNA …
societies. The exploration of brain epigenomes, which consist of multiple forms of DNA …