The role of diet and dietary patterns in Parkinson's disease

E Knight, T Geetha, D Burnett, JR Babu - Nutrients, 2022 - mdpi.com
Parkinson's Disease (PD) is a neurodegenerative disorder associated with diminished
nutrition status and decreased quality of life. While the prevalence of PD is expected to …

Mitochondria-targeted antioxidants, an innovative class of antioxidant compounds for neurodegenerative diseases: perspectives and limitations

M Fields, A Marcuzzi, A Gonelli, C Celeghini… - International journal of …, 2023 - mdpi.com
Neurodegenerative diseases comprise a wide spectrum of pathologies characterized by
progressive loss of neuronal functions and structures. Despite having different genetic …

Cognitive impairment and dementia in Parkinson disease

JG Goldman, E Sieg - Clinics in geriatric medicine, 2020 - geriatric.theclinics.com
Cognitive impairment is a frequent nonmotor symptom in Parkinson disease (PD), often
associated with poor outcomes and reduced quality of life. 1–3 Cognitive impairment in PD …

Digital biomarkers for non-motor symptoms in Parkinson's disease: the state of the art

JM Janssen Daalen, R van den Bergh, EM Prins… - NPJ Digital …, 2024 - nature.com
Digital biomarkers that remotely monitor symptoms have the potential to revolutionize
outcome assessments in future disease-modifying trials in Parkinson's disease (PD), by …

Integrating the roles of midbrain dopamine circuits in behavior and neuropsychiatric disease

APF Chen, L Chen, TA Kim, Q **ong - Biomedicines, 2021 - mdpi.com
Dopamine (DA) is a behaviorally and clinically diverse neuromodulator that controls CNS
function. DA plays major roles in many behaviors including locomotion, learning, habit …

The effect of the ketogenic diet on the therapy of neurodegenerative diseases and its impact on improving cognitive functions

K Grochowska, A Przeliorz - Dementia and geriatric cognitive disorders …, 2022 - karger.com
The ketogenic diet (KD) is a high-fat and low-carbohydrate diet with controlled amounts of
protein. The use of drastic caloric restriction or ultralow-carbohydrate diets increases the …

Female rats are resistant to cognitive, motor and dopaminergic deficits in the reserpine-induced progressive model of Parkinson's disease

AC Lima, YSR Meurer, VS Bioni… - Frontiers in aging …, 2021 - frontiersin.org
Parkinson's disease (PD) is the second most common neurodegenerative disease. The
main symptoms are motor signs such as resting tremor and difficulty in initializing …

Assessment tools for cognitive performance in Parkinson's disease and its genetic contributors

LX Cao, WL Kong, P Chan, W Zhang, MJ Morris… - Frontiers in …, 2024 - frontiersin.org
Background We have shown that genetic factors associating with motor progression of
Parkinson's disease (PD), but their roles in cognitive function is poorly understood. One …

PPARγ and cognitive performance

M d'Angelo, V Castelli, M Catanesi… - International Journal of …, 2019 - mdpi.com
Recent findings have led to the discovery of many signaling pathways that link nuclear
receptors with human conditions, including mental decline and neurodegenerative …

Frailty and cognitive impairment in Parkinson's disease: a systematic review

MC Sousa-Fraguas, G Rodríguez-Fuentes… - Neurological …, 2022 - Springer
Background Frailty can lead to increased vulnerability in older people and patients with
Parkinson's disease (pwPD) and worsen their health conditions. These patients can also …