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[HTML][HTML] The NLRP3 inflammasome as a target for sensorineural hearing loss
Sensorineural hearing loss is the most common type of hearing loss in adults and occurs
due to damage of the inner ear caused by a range of factors including ageing, excessive …
due to damage of the inner ear caused by a range of factors including ageing, excessive …
Targeting tumor physical microenvironment for improved radiotherapy
Radiotherapy has led to important clinical advances; existing cancer radiotherapy resistance
is one remaining major challenge. Recently, biophysical cues in the tumor …
is one remaining major challenge. Recently, biophysical cues in the tumor …
Normalizing granuloma vasculature and matrix improves drug delivery and reduces bacterial burden in tuberculosis-infected rabbits
Host-directed therapies (HDTs) represent an emerging approach for bacterial clearance
during tuberculosis (TB) infection. While most HDTs are designed and implemented for …
during tuberculosis (TB) infection. While most HDTs are designed and implemented for …
Angiotensin II receptor inhibition ameliorates liver fibrosis and enhances hepatocellular carcinoma infiltration by effector T cells
L Gu, Y Zhu, M Lee, A Nguyen, NT Ryu**… - Proceedings of the …, 2023 - pnas.org
Although viral hepatocellular carcinoma (HCC) is declining, nonviral HCC, which often is the
end stage of nonalcoholic or alcoholic steatohepatitis (NASH, ASH), is on an upward …
end stage of nonalcoholic or alcoholic steatohepatitis (NASH, ASH), is on an upward …
Soft and stretchable organic bioelectronics for continuous intraoperative neurophysiological monitoring during microsurgery
W Zhou, Y Jiang, Q Xu, L Chen, H Qiao… - Nature Biomedical …, 2023 - nature.com
In microneurosurgery, it is crucial to maintain the structural and functional integrity of the
nerve through continuous intraoperative identification of neural anatomy. To this end, here …
nerve through continuous intraoperative identification of neural anatomy. To this end, here …
Potential molecular biomarkers of vestibular schwannoma growth: progress and prospects
Y Zhang, J Long, J Ren, X Huang, P Zhong… - Frontiers in …, 2021 - frontiersin.org
Vestibular schwannomas (VSs, also known as acoustic neuromas) are relatively rare benign
brain tumors stem from the Schwann cells of the eighth cranial nerve. Tumor growth is the …
brain tumors stem from the Schwann cells of the eighth cranial nerve. Tumor growth is the …
Sporadic vestibular schwannoma size and location do not correlate with the severity of hearing loss at initial presentation
Vestibular schwannoma (VS) is a non-malignant intracranial neoplasm arising from the
vestibular branch of the 8th cranial nerve; sensorineural hearing loss (SNHL) is the most …
vestibular branch of the 8th cranial nerve; sensorineural hearing loss (SNHL) is the most …
Probing the physical hallmarks of cancer
The physical microenvironment plays a crucial role in tumor development, progression,
metastasis and treatment. Recently, we proposed four physical hallmarks of cancer, with …
metastasis and treatment. Recently, we proposed four physical hallmarks of cancer, with …
Inhibiting AGTR1 reduces AML burden and protects the heart from cardiotoxicity in mouse models
Y Pan, C Wang, WX Zhou, Y Shi, XD Meng… - Science translational …, 2024 - science.org
Clinical treatment of acute myeloid leukemia (AML) largely relies on intensive
chemotherapy. However, the application of chemotherapy is often hindered by cardiotoxicity …
chemotherapy. However, the application of chemotherapy is often hindered by cardiotoxicity …
Immune profiling of secreted factors from human vestibular schwannoma cells and tumor‐associated macrophages
Objectives This study compared the immune‐related secretory capacity of human vestibular
schwannoma (VS) and tumor‐assisted macrophages (TAMs) with their normal counterparts …
schwannoma (VS) and tumor‐assisted macrophages (TAMs) with their normal counterparts …