Over more than a century of research has established the fact that sleep benefits the
retention of memory. In this review we aim to comprehensively cover the field of “sleep and …

Sleep disturbances (SD) accompany many neurodevelopmental disorders, suggesting SD is
a transdiagnostic process that can account for behavioral deficits and influence underlying …

Sleep is conserved from invertebrates to vertebrates, and is tightly regulated in a
homeostatic manner. The molecular and cellular mechanisms that determine the amount of …

Recently, the transgenerational toxicity of nanoplastics has received increasing attention.
Caenorhabditis elegans is a useful model to assess the transgenerational toxicity of different …

Sleep is an essential behavioral state. It is induced by conserved sleep-active neurons that
express GABA. However, little is known about how sleep neuron function is determined and …

Background Sleep is an essential behavior that is found in all animals that have a nervous
system. Neural activity is thought to control sleep, but little is known about the identity and …

Although extracellular matrices function as protective barriers to many types of
environmental insult, their role in sensing stress and regulating adaptive gene induction …

The genetic basis of sleep regulation remains poorly understood. In C. elegans, cellular
stress induces sleep through epidermal growth factor (EGF)-dependent activation of the EGF …

Background Biological timing mechanisms that integrate cyclical and successive processes
are not well understood. C. elegans molting cycles involve rhythmic cellular and animal …

Progress has been made in the elucidation of sleep and wakefulness regulation at the
neurocircuit level,. However, the intracellular signalling pathways that regulate sleep and the …