• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

LRRC4 is a novel relatively specific gene, which displays significant down-regulation in
primary brain tumor biopsies and has the potential to suppress brain tumor growth. In this …

Importance Infective endocarditis occurs in approximately 15 of 100 000 people in the
United States and has increased in incidence. Clinicians must make treatment decisions …

According to World Health Organization statistics of 2011, infectious diseases remain in the
top five causes of mortality worldwide. However, despite sophisticated research tools for …

The content of these European Society of Cardiology (ESC) Guidelines has been published
for personal and educational use only. No commercial use is authorized. No part of the ESC …

The traditional identification of bacteria on the basis of phenotypic characteristics is
generally not as accurate as identification based on genotypic methods. Comparison of the …

Background Dysbiosis of the oral microbiome can lead to local oral disease and potentially
to cancers of the head, neck, and digestive tract. However, little is known regarding …

The BSAC guidelines on treatment of infectious endocarditis (IE) were last published in
2004. The guidelines presented here have been updated and extended to reflect …

Since the division of the Streptococcus genus into enterococci, lactococci, and streptococci
in 1984, many changes in the nomenclature and taxonomy of the Streptococcus genus have …

The clinical features of this complex infection have changed in the past several decades. It is
now an infection of older people, and mitral-valve prolapse is the most common …