Aging is characterized by systemic chronic inflammation, which is accompanied by cellular
senescence, immunosenescence, organ dysfunction, and age-related diseases. Given the …

Since the evolution of the aerobic metabolism, reactive oxygen species (ROS) have
represented significant challenges to diverse life forms. In recent decades, increasing …

Naked mole‐rats (NMRs) have exceptional longevity and are resistant to age‐related
physiological decline and diseases. Given the role of cellular senescence in aging, we …

Many biological mechanisms of aging well converge with radiation's biological effects. We
used scientific insights from the field of aging to establish a novel hypoxic-hypercapnic …

Age-related hearing loss affects a large and growing segment of the population, with
profound impacts on quality of life. Age-related pathology of the cochlea—the mammalian …

The naked mole-rat (NMR) Heterocephalus glaber (from the Greek/latin words ἕτερος,
heteros= divergent, κεφαλή, kephalē= head and glabra= hairless) was first described by …

Bats, notable as the only flying mammals, serve as natural reservoir hosts for various highly
pathogenic viruses in humans (eg, SARS-CoV and Ebola virus). Furthermore, bats exhibit …

The white-footed deermouse Peromyscus leucopus, a long-lived rodent, is a key reservoir in
North America for agents of several zoonoses, including Lyme disease, babesiosis …

The white-footed deermouse Peromyscus leucopus, a long-lived rodent, is a key reservoir
for agents of several zoonoses, including Lyme disease. While persistently infected, this …

The search for solutions to the vagaries of aging have, historically, been akin to searching at
night in the bright light under street lamps by utilizing the few preexisting and well …