A systematic review of the applications of artificial intelligence and machine learning in autoimmune diseases

IS Stafford, M Kellermann, E Mossotto, RM Beattie… - NPJ digital …, 2020‏ - nature.com
Autoimmune diseases are chronic, multifactorial conditions. Through machine learning (ML),
a branch of the wider field of artificial intelligence, it is possible to extract patterns within …

Evolving insights into the cellular and molecular pathogenesis of fibrosis in systemic sclerosis

B Korman - Translational Research, 2019‏ - Elsevier
Systemic sclerosis (SSc, scleroderma) is a complex multisystem disease characterized by
autoimmunity, vasculopathy, and most notably, fibrosis. Multiple lines of evidence …

Artificial intelligence for predicting treatment responses in autoimmune rheumatic diseases: advancements, challenges, and future perspectives

Y Yang, Y Liu, Y Chen, D Luo, K Xu… - Frontiers in …, 2024‏ - frontiersin.org
Autoimmune rheumatic diseases (ARD) present a significant global health challenge
characterized by a rising prevalence. These highly heterogeneous diseases involve …

Machine learning in rheumatic diseases

M Jiang, Y Li, C Jiang, L Zhao, X Zhang… - Clinical Reviews in …, 2021‏ - Springer
With advances in information technology, the demand for using data science to enhance
healthcare and disease management is rapidly increasing. Among these technologies …

Existing and novel biomarkers for precision medicine in systemic sclerosis

PJ Wermuth, S Piera-Velazquez… - Nature Reviews …, 2018‏ - nature.com
The discovery and validation of biomarkers resulting from technological advances in the
analysis of genomic, transcriptomic, lipidomic and metabolomic pathways involved in the …

Current and future perspectives on management of systemic sclerosis-associated interstitial lung disease

O Distler, ER Volkmann… - Expert review of …, 2019‏ - Taylor & Francis
ABSTRACT Introduction: Systemic sclerosis (SSc) is a rare and complex connective tissue
disease characterized by fibrosis of the skin and internal organs. Interstitial lung disease …

[HTML][HTML] The use and utility of machine learning in achieving precision medicine in systemic sclerosis: a narrative review

F Bonomi, S Peretti, G Lepri, V Venerito… - Journal of Personalized …, 2022‏ - mdpi.com
Background: Systemic sclerosis (SSc) is a rare connective tissue disease that can affect
different organs and has extremely heterogenous presentations. This complexity makes it …

Perspective to precision medicine in scleroderma

K Komura, K Yanaba, JD Bouaziz, A Yoshizaki… - Frontiers in …, 2024‏ - frontiersin.org
Systemic sclerosis (SSc) is a rare and heterogeneous disease with no relevant
environmental trigger or significant responsible gene. It has been and will continue to be …

TGFB1-mediated gliosis in multiple sclerosis spinal cords is favored by the regionalized expression of HOXA5 and the age-dependent decline in androgen receptor …

S Nataf, M Guillen, L Pays - International Journal of Molecular Sciences, 2019‏ - mdpi.com
In multiple sclerosis (MS) patients with a progressive form of the disease, spinal cord (SC)
functions slowly deteriorate beyond age 40. We previously showed that in the SC of these …

Systematic analysis of the literature in search of defining systemic sclerosis subsets

T Nevskaya, JE Pope, MA Turk, J Shu… - The Journal of …, 2021‏ - jrheum.org
Objective Systemic sclerosis (SSc) is a multisystem disease with heterogeneity in
presentation and prognosis. An international collaboration to develop new SSc subset …