The pancreas avidly takes up and synthesizes the amino acid asparagine (Asn), in part, to
maintain an active translational machinery that requires incorporation of the amino acid. The …

Pathologists are adopting whole slide images (WSIs) for diagnostic purposes. While doing
so, pathologists should have all the information needed to make best diagnoses rapidly …

The mechanisms by which drugs induce pancreatitis are unknown. A definite cause of
pancreatitis is due to the antiepileptic drug valproic acid (VPA). On the basis of three crucial …

Mice lacking Sirt2 spontaneously develop tumors in multiple organs, as well as when
expressed in combination with oncogenic Kras G12D, leading to pancreatic tumors. Here …

It is well known that pancreatic recovery after a single episode of injury such as an isolated
bout of pancreatitis occurs rapidly. It is unclear, however, what changes are inflicted in such …

Acute pancreatitis is an extremely painful and life-threatening inflammatory disease of the
exocrine pancreas (57, 100). A sobering point for both clinicians and researchers is that the …

Background & Aims: Pancreatitis is an inflammatory disease of the exocrine pancreas and is
a known risk factor for pancreatic ductal adenocarcinoma (PDAC). We previously identified …

While skin, liver and gut have the ability to regenerate and heal, other organs such as heart
and brain do not display similar regenerative capacities. The adult pancreas displays a …

Islet cell quantification and function is important for develo** novel therapeutic
interventions for diabetes. Existing methods of pancreatic islet segmentation in …

The clustering phenomenon often appears in histopathology image, some cells overlap or
touch together to from a big area. It is necessary to design an effective algorithm to separate …