8-hydroxy-2′-deoxyguanosine (8-OH-dG) was first reported in 1984 as a major form of
oxidative DNA damage product by heated sugar, Fenton-type reagents and X-irradiation in …

In living cells reactive oxygen species (ROS) are formed continuously as a consequence of
metabolic and other biochemical reactions as well as external factors. Some ROS have …

Commonly consumed foods and beverages can contain chemicals with reported
carcinogenic activity in rodent models. Moreover, exposures to some of these substances …

Catechols can undergo a variety of chemical reactions. In this review, we particularly focus
on complex formations and the redox chemistry of catechols, which play an inportant role in …

Benzene causes acute myeloid leukemia and probably other hematological malignancies.
As benzene also causes hematotoxicity even in workers exposed to levels below the US …

Objective Benzene, as a volatile organic compound, is known as one of the main air
pollutants in the environment. The aim of this review is to summarize all available evidences …

Acute myeloid leukemia (AML) is a group of hematological diseases, phenotypic and
genetically heterogeneous, characterized by abnormal accumulation of blast cells in the …

The key characteristics (KC) of human carcinogens provide a uniform approach to
evaluating mechanistic evidence in cancer hazard identification. Refinements to the …

To investigate the ability of the production of H2O2 by polyphenols, we incubated various
phenolic compounds and natural polyphenols under a quasi-physiological pH and …

The family of human peroxidases described includes myeloperoxidase, eosinophil
peroxidase, uterine peroxidase, lactoperoxidase, salivary peroxidase, thyroid peroxidase …