Paleoproteomics

C Warinner, K Korzow Richter, MJ Collins - Chemical reviews, 2022 - ACS Publications
Paleoproteomics, the study of ancient proteins, is a rapidly growing field at the intersection of
molecular biology, paleontology, archaeology, paleoecology, and history. Paleoproteomics …

Journey of Rosmarinic acid as biomedicine to nano-biomedicine for treating cancer: Current strategies and future perspectives

MVNL Chaitanya, AK Ramanunny, MR Babu, M Gulati… - Pharmaceutics, 2022 - mdpi.com
Rosmarinic acid (RA) is a polyphenolic metabolite found in various culinary, dietary sources,
and medicinal plants like Coleus scutellarioides (Linn) Benth., Lavandula angustifolia Linn …

Fluorogenic probes for live-cell imaging of the cytoskeleton

G Lukinavičius, L Reymond, E D'este, A Masharina… - Nature …, 2014 - nature.com
We introduce far-red, fluorogenic probes that combine minimal cytotoxicity with excellent
brightness and photostability for fluorescence imaging of actin and tubulin in living cells …

The quantitative proteome of a human cell line

M Beck, A Schmidt, J Malmstroem… - Molecular systems …, 2011 - embopress.org
The generation of mathematical models of biological processes, the simulation of these
processes under different conditions, and the comparison and integration of multiple data …

Rxrx1: A dataset for evaluating experimental batch correction methods

M Sypetkowski, M Rezanejad… - Proceedings of the …, 2023 - openaccess.thecvf.com
High-throughput screening techniques are commonly used to obtain large quantities of data
in many fields of biology. It is well known that artifacts arising from variability in the technical …

Merging bioactivity predictions from cell morphology and chemical fingerprint models using similarity to training data

S Seal, H Yang, MA Trapotsi, S Singh… - Journal of …, 2023 - Springer
The applicability domain of machine learning models trained on structural fingerprints for the
prediction of biological endpoints is often limited by the lack of diversity of chemical space of …

Rosmarinic acid exerts an anticancer effect on osteosarcoma cells by inhibiting DJ-1 via regulation of the PTEN-PI3K-Akt signaling pathway

Z Ma, J Yang, Y Yang, X Wang, G Chen, A Shi, Y Lu… - Phytomedicine, 2020 - Elsevier
Background Osteosarcoma is the most common type of primary malignant bone tumor. This
disease has exhibited a progressively lower survival rate over the past several decades …

Split and merge watershed: A two-step method for cell segmentation in fluorescence microscopy images

M Gamarra, E Zurek, HJ Escalante, L Hurtado… - … signal processing and …, 2019 - Elsevier
The development of advanced techniques in medical imaging has allowed scanning of the
human body to microscopic levels, making research on cell behavior more complex and …

Far upstream element binding protein 1: a commander of transcription, translation and beyond

J Zhang, QM Chen - Oncogene, 2013 - nature.com
The far upstream binding protein 1 (FBP1) was first identified as a DNA-binding protein that
regulates c-Myc gene transcription through binding to the far upstream element (FUSE) in …

The master regulator FUBP1: its emerging role in normal cell function and malignant development

L Debaize, MB Troadec - Cellular and Molecular Life Sciences, 2019 - Springer
Abstract The human Far Upstream Element (FUSE) Binding Protein 1 (FUBP1) is a
multifunctional DNA-and RNA-binding protein involved in diverse cellular processes. FUBP1 …