Enhancing the therapeutic efficacy of nanoparticles for cancer treatment using versatile targeted strategies
Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …
Chemodynamic therapy via fenton and fenton‐like nanomaterials: strategies and recent advances
Chemodynamic therapy (CDT), a novel cancer therapeutic strategy defined as the treatment
using Fenton or Fenton‐like reaction to produce• OH in the tumor region, was first proposed …
using Fenton or Fenton‐like reaction to produce• OH in the tumor region, was first proposed …
Do** engineering to modulate lattice and electronic structure for enhanced piezocatalytic therapy and ferroptosis
B Tian, R Tian, S Liu, Y Wang, S Gai, Y **e… - Advanced …, 2023 - Wiley Online Library
Piezocatalytic therapy, which generates reactive oxygen species (ROS) under mechanical
force, has garnered extensive attention for its use in cancer therapy owing to its deep tissue …
force, has garnered extensive attention for its use in cancer therapy owing to its deep tissue …
Manipulating intratumoral fenton chemistry for enhanced chemodynamic and chemodynamic‐synergized multimodal therapy
Chemodynamic therapy (CDT) uses the tumor microenvironment‐assisted intratumoral
Fenton reaction for generating highly toxic hydroxyl free radicals (• OH) to achieve selective …
Fenton reaction for generating highly toxic hydroxyl free radicals (• OH) to achieve selective …
Engineering nanomedicine for glutathione depletion-augmented cancer therapy
Y **ong, C **ao, Z Li, X Yang - Chemical Society Reviews, 2021 - pubs.rsc.org
Glutathione (GSH), the main redox buffer, has long been recognized as a pivotal modulator
of tumor initiation, progression and metastasis. It is also implicated in the resistance of …
of tumor initiation, progression and metastasis. It is also implicated in the resistance of …
Biomedicine meets Fenton chemistry
Since the first connection between Fenton chemistry and biomedicine, numerous studies
have been presented in this field. Comprehensive presentation of the guidance from Fenton …
have been presented in this field. Comprehensive presentation of the guidance from Fenton …
Copper-induced tumor cell death mechanisms and antitumor theragnostic applications of copper complexes
Y Jiang, Z Huo, X Qi, T Zuo, Z Wu - Nanomedicine, 2022 - Taylor & Francis
Recent studies found that unbalanced copper homeostasis affect tumor growth, causing
irreversible damage. Copper can induce multiple forms of cell death, including apoptosis …
irreversible damage. Copper can induce multiple forms of cell death, including apoptosis …
Nanocatalytic theranostics with glutathione depletion and enhanced reactive oxygen species generation for efficient cancer therapy
Chemodynamic therapy (CDT) is an emerging therapy method that kills cancer cells by
converting intracellular hydrogen peroxide (H2O2) into highly toxic hydroxyl radicals (• OH) …
converting intracellular hydrogen peroxide (H2O2) into highly toxic hydroxyl radicals (• OH) …
Enhanced chemodynamic therapy by Cu–Fe peroxide nanoparticles: tumor microenvironment-mediated synergistic Fenton reaction
An urgent need in chemodynamic therapy (CDT) is to achieve high Fenton catalytic
efficiency at small doses of CDT agents. However, simple general promotion of the Fenton …
efficiency at small doses of CDT agents. However, simple general promotion of the Fenton …
Tumor-generated reactive oxygen species storm for high-performance ferroptosis therapy
Ferroptosis therapy (FT) efficacy of tumors suffers from a relatively low concentration of
Fenton agents, limited hydrogen peroxide (H2O2) content, and insufficient acidity in the …
Fenton agents, limited hydrogen peroxide (H2O2) content, and insufficient acidity in the …