Towards a future where Alzheimer's disease pathology is stopped before the onset of dementia
WM van der Flier, ME de Vugt, EMA Smets, M Blom… - Nature aging, 2023 - nature.com
Alzheimer's disease (AD) is a major healthcare challenge with no curative treatment at
present. To address this challenge, we need a paradigm shift, where we focus on pre …
present. To address this challenge, we need a paradigm shift, where we focus on pre …
Is Alzheimer disease a disease?
AD Korczyn, LT Grinberg - Nature Reviews Neurology, 2024 - nature.com
Dementia, a prevalent condition among older individuals, has profound societal
implications. Extensive research has resulted in no cure for what is perceived as the most …
implications. Extensive research has resulted in no cure for what is perceived as the most …
Mental health care for older adults: recent advances and new directions in clinical practice and research
CF Reynolds 3rd, DV Jeste, PS Sachdev… - World …, 2022 - Wiley Online Library
The world's population is aging, bringing about an ever‐greater burden of mental disorders
in older adults. Given multimorbidities, the mental health care of these people and their …
in older adults. Given multimorbidities, the mental health care of these people and their …
Mechanisms of sex differences in Alzheimer's disease
C Lopez-Lee, ERS Torres, G Carling, L Gan - Neuron, 2024 - cell.com
Alzheimer's disease (AD) and the mechanisms underlying its etiology and progression are
complex and multifactorial. The higher AD risk in women may serve as a clue to better …
complex and multifactorial. The higher AD risk in women may serve as a clue to better …
Alzheimer's disease
In this Seminar, we highlight the main developments in the field of Alzheimer's disease. The
most recent data indicate that, by 2050, the prevalence of dementia will double in Europe …
most recent data indicate that, by 2050, the prevalence of dementia will double in Europe …
Nutrition, physical activity, and other lifestyle factors in the prevention of cognitive decline and dementia
LJ Dominguez, N Veronese, L Vernuccio, G Catanese… - Nutrients, 2021 - mdpi.com
Multiple factors combined are currently recognized as contributors to cognitive decline. The
main independent risk factor for cognitive impairment and dementia is advanced age …
main independent risk factor for cognitive impairment and dementia is advanced age …
[HTML][HTML] Dementia prevention in memory clinics: recommendations from the European task force for brain health services
Observational population studies indicate that prevention of dementia and cognitive decline
is being accomplished, possibly as an unintended result of better vascular prevention and …
is being accomplished, possibly as an unintended result of better vascular prevention and …
Active aging and public health: evidence, implications, and opportunities
By 2050, 20% of the world's population will be over the age of 65 years, with projections that
80% of older adults will be living in low-to middle-income countries. Physical inactivity and …
80% of older adults will be living in low-to middle-income countries. Physical inactivity and …
Designing the next-generation clinical care pathway for Alzheimer's disease
The reconceptualization of Alzheimer's disease (AD) as a clinical and biological construct
has facilitated the development of biomarker-guided, pathway-based targeted therapies …
has facilitated the development of biomarker-guided, pathway-based targeted therapies …
Effects of intensive lifestyle changes on the progression of mild cognitive impairment or early dementia due to Alzheimer's disease: a randomized, controlled clinical …
D Ornish, C Madison, M Kivipelto, C Kemp… - Alzheimer's Research & …, 2024 - Springer
Background Evidence links lifestyle factors with Alzheimer's disease (AD). We report the first
randomized, controlled clinical trial to determine if intensive lifestyle changes may …
randomized, controlled clinical trial to determine if intensive lifestyle changes may …