More than two decades have elapsed since the publication of the first genome sequence of
Mycobacterium tuberculosis (Mtb) which, shortly thereafter, enabled methods to determine …

Tuberculosis (TB), an infectious disease caused by the bacterium Mycobacterium
tuberculosis (Mtb), has burdened vulnerable populations in modern day societies for …

Copper‐catalyzed cross‐couplings of aryl halides and nucleophiles, traditionally called
Ullmann‐type coupling reactions, were initially reported by Ullmann et al. from 1901—1929 …

In this study, we reported a novel oxazole-based NIR probe for the detection of Cu 2+ and S
2− ions sequentially in buffer solution. The probe showed a" turn-off" fluorescent response …

Guanine nucleotides are required for growth and viability of cells due to their structural role
in DNA and RNA, and their regulatory roles in translation, signal transduction, and cell …

Tuberculosis (TB) has been considered as the highly chronic, contagious and infectious
disorder caused by Mycobacterium tuberculosis (Mtb). Every year more than 10 million …

Abstract Decaprenyl-phosphoryl-ribose 2′-epimerase (DprE1) inhibitors are an innovative
and futuristic orally active group of antituberculosis agents. A few DprE1 inhibitors are in the …

In this study, p-tert-butyl at position 2 and acetamide bridged 4-substituted
piperazine/piperidine at position 5 bearing benzoxazole derivatives were evaluated for their …

Allosteric regulation of inosine 5′-monophosphate dehydrogenase (IMPDH), an essential
enzyme of purine metabolism, contributes to the homeostasis of adenine and guanine …

Tuberculosis (TB) continues to claim the lives of around 1.7 million people per year. Most
concerning are the reports of multidrug drug resistance. Paradoxically, this global health …