Colorectal neoplasms are one of the deadliest diseases among all cancers worldwide.
Thymoquinone (TQ) is a natural compound of Nigella sativa that has been used in traditional …

Cancer is a leading cause of death in the world today. In addition to the side effects of the
chemotherapeutic drugs used to treat cancer, the development of resistance to the drugs …

Mathematical models are used to characterize and optimize drug release in drug delivery
systems (DDS). One of the most widely used DDS is the poly (lactic-co-glycolic acid)(PLGA) …

Melanoma is a form of skin cancer that starts in melanocytes. Rampant chemo-resistance,
metastasis, and inability to cross the skin barriers and accumulate within the tumor …

Colon cancer is the third most common cancer worldwide, with high mortality. Adverse side
effects and chemoresistance of the first-line chemotherapy 5-fluorouracil (5-FU) have …

Drug resistance and off-target toxicity are two of the greatest challenges to
chemotherapeutic melanoma treatments. Nitric oxide (NO) represents an attractive …

In this research, we have modified tocopheryl polyethylene glycol succinate (TPGS) to a
redox-sensitive material, denoted as TPGS-SH, and employed the same to develop dual …

Nature serves as a priceless source for phytomedicines to treat different types of cancer,
including hepatocellular carcinoma (HCC). Apocynin (APO), an anti-cancer phytomedicine …

This study aimed to evaluate the effect of thiolated α-cyclodextrin (α-CD-SH) on the cellular
uptake of its payload. For this purpose, α-CD was thiolated using phosphorous pentasulfide …

The outbreak of a fatal black fungus infection after the resurgence of the cadaverous COVID-
19 has exhorted scientists worldwide to develop a nutshell by repurposing or designing new …