The allene functionality has participated in one of the most exciting voyages in organic
chemistry, from chemical curiosities to a recurring building block in modern organic …

Conspectus So far, over 150 natural products and pharmaceuticals containing an allene
moiety have been identified. During the last two decades, allenes have also been …

Chiral organophosphorous compounds are very important in catalysis, organic syntheses,
and medicinal chemistry. However, catalytic enantioselective protocols for the axially chiral …

Catalytic 1, 4-dicarbofunctionalization of 1, 3-enynes is a powerful strategy for the synthesis
of polysubstituted allenes. Despite impressive progress, such a strategy is still restricted to …

Because of its wide applicability in the synthesis of diverse unsaturated building blocks,
allene–alkyne (AA) coupling has emerged as a powerful methodology to drive useful …

A MnI‐catalyzed regioselective C− H allenylation is reported that allows a broad range of 2‐
allenylindoles to be synthesized regioselectively on a gram scale under simple conditions …

Enabled by the newly developed ligand, Ming-Phos, the first example of palladium-
catalyzed highly enantioselective coupling of racemic propargylic benzoates with …

Efficient enantioselective construction of fully substituted allenes from simple starting
materials is still a fundamental challenge due to the difficulty to discriminate between the …

Allenes are versatile synthons in organic synthesis and medicinal chemistry because of their
diverse reactivities. Catalytic 1, 4-hydrosilylation of 1, 3-enynes may present the …

A copper-catalyzed trifluoromethylthio-arylsulfonylation between 1, 3-enynes, AgSCF3,
aryldiazonium tetrafluoroborates, and SO2 (from SOgen) is presented, which could …