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Exercise metabolism and adaptation in skeletal muscle
Viewing metabolism through the lens of exercise biology has proven an accessible and
practical strategy to gain new insights into local and systemic metabolic regulation. Recent …
practical strategy to gain new insights into local and systemic metabolic regulation. Recent …
Crosstalk between metabolism and circadian clocks
Humans, like all mammals, partition their daily behaviour into activity (wakefulness) and rest
(sleep) phases that differ largely in their metabolic requirements. The circadian clock …
(sleep) phases that differ largely in their metabolic requirements. The circadian clock …
Communicating clocks shape circadian homeostasis
BACKGROUND Life-forms ranging from bacteria to humans are programmed by circadian
clocks—mechanisms that impose an~ 24-hour rhythmicity on biology in harmony with …
clocks—mechanisms that impose an~ 24-hour rhythmicity on biology in harmony with …
Transcriptional control of energy metabolism by nuclear receptors
Transcriptional regulation of catabolic pathways is a central mechanism by which cells
respond to physiological cues to generate the energy required for anabolic pathways …
respond to physiological cues to generate the energy required for anabolic pathways …
Circadian rhythms and exercise—re-setting the clock in metabolic disease
Perturbed diurnal rhythms are becoming increasingly evident as deleterious events in the
pathology of metabolic diseases. Exercise is well characterized as a crucial intervention in …
pathology of metabolic diseases. Exercise is well characterized as a crucial intervention in …
[HTML][HTML] Regulation of skeletal muscle function by amino acids
Y Kamei, Y Hatazawa, R Uchitomi, R Yoshimura… - Nutrients, 2020 - mdpi.com
Amino acids are components of proteins that also exist free-form in the body; their functions
can be divided into (1) nutritional,(2) sensory, and (3) biological regulatory roles. The …
can be divided into (1) nutritional,(2) sensory, and (3) biological regulatory roles. The …
Metabolism and exercise: the skeletal muscle clock takes centre stage
Circadian rhythms that influence mammalian homeostasis and overall health have received
increasing interest over the past two decades. The molecular clock, which is present in …
increasing interest over the past two decades. The molecular clock, which is present in …
Time of exercise specifies the impact on muscle metabolic pathways and systemic energy homeostasis
While the timing of food intake is important, it is unclear whether the effects of exercise on
energy metabolism are restricted to unique time windows. As circadian regulation is key to …
energy metabolism are restricted to unique time windows. As circadian regulation is key to …
[HTML][HTML] Diet for the prevention and management of sarcopenia
Sarcopenia is a geriatric condition characterized by a progressive loss of skeletal muscle
mass and strength, with an increased risk of adverse health outcomes (eg, falls, disability …
mass and strength, with an increased risk of adverse health outcomes (eg, falls, disability …
Foundations of circadian medicine
The circadian clock is an evolutionarily highly conserved endogenous timing program that
structures physiology and behavior according to the time of day. Disruption of circadian …
structures physiology and behavior according to the time of day. Disruption of circadian …