Abstract S‐adenosyl‐l‐methionine (SAM) is a high‐value compound widely used in the
treatment of various diseases. SAM can be produced through fermentation, but further …

Recombinant protein production in Pichia pastoris is based on alcohol oxidase promoters
which are regulated by methanol. However, the use of methanol has several disadvantages …

Abstract S‐Adenosyl‐l‐methionine (SAM) is an important small molecule compound widely
used in treating various diseases. Although l‐methionine is generally used, the low‐cost dl …

As an important biological methyl group donor, S-adenosyl-l-methionine is used as
nutritional supplement or drug for various diseases, but bacterial strains that can efficiently …

Glutathione (GSH) and S-adenosyl methionine (SAM) have been applied as liver-protective
factors to prevent and treat many different liver damages and diseases. Due to their low …

S-Adenosylmethionine (SAM) is a natural metabolite having important uses in the treatment
of various diseases. To develop a simple and effective way to produce SAM, immobilized …

Two genes encoding methionine adenosyltransferase, SAM2 from Saccharomyces
cerevisiae and metK from Corynebacterium glutamicum, were individually cloned into pDXW …

This study sought to develop a cost-effective biological catalysis process for S-adenosyl-l-
methionine (SAM) production. During the process, a mixture of d-methionine (d-Met) and l …

The high-level and cost-effective production of biopharmaceuticals and other compounds of
commercial interest is possible because of advancements in molecular biology and …

ABSTRACT S-adenosylmethionine (SAMe) is the most common methyl donor found in living
organisms. It is the second most common cellular enzyme substrate and is an essential …