What is flux balance analysis?

JD Orth, I Thiele, BØ Palsson - Nature biotechnology, 2010 - nature.com
What is flux balance analysis? | Nature Biotechnology Skip to main content Thank you for
visiting nature.com. You are using a browser version with limited support for CSS. To obtain the …

A travel guide to Cytoscape plugins

R Saito, ME Smoot, K Ono, J Ruscheinski, PL Wang… - Nature …, 2012 - nature.com
Cytoscape is open-source software for integration, visualization and analysis of biological
networks. It can be extended through Cytoscape plugins, enabling a broad community of …

Large-scale gene function analysis with the PANTHER classification system

H Mi, A Muruganujan, JT Casagrande, PD Thomas - Nature protocols, 2013 - nature.com
The PANTHER (protein annotation through evolutionary relationship) classification system
(http://www. pantherdb. org/) is a comprehensive system that combines gene function …

The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored

D Szklarczyk, A Franceschini, M Kuhn… - Nucleic acids …, 2010 - academic.oup.com
An essential prerequisite for any systems-level understanding of cellular functions is to
correctly uncover and annotate all functional interactions among proteins in the cell. Toward …

PANTHER in 2013: modeling the evolution of gene function, and other gene attributes, in the context of phylogenetic trees

H Mi, A Muruganujan, PD Thomas - Nucleic acids research, 2012 - academic.oup.com
The data and tools in PANTHER—a comprehensive, curated database of protein families,
trees, subfamilies and functions available at http://pantherdb. org—have undergone …

Systems biology and multi-omics integration: viewpoints from the metabolomics research community

FR Pinu, DJ Beale, AM Paten, K Kouremenos… - Metabolites, 2019 - mdpi.com
The use of multiple omics techniques (ie, genomics, transcriptomics, proteomics, and
metabolomics) is becoming increasingly popular in all facets of life science. Omics …

BiGG Models: A platform for integrating, standardizing and sharing genome-scale models

ZA King, J Lu, A Dräger, P Miller… - Nucleic acids …, 2016 - academic.oup.com
Genome-scale metabolic models are mathematically-structured knowledge bases that can
be used to predict metabolic pathway usage and growth phenotypes. Furthermore, they can …

COPASI—a complex pathway simulator

S Hoops, S Sahle, R Gauges, C Lee, J Pahle… - …, 2006 - academic.oup.com
Motivation: Simulation and modeling is becoming a standard approach to understand
complex biochemical processes. Therefore, there is a big need for software tools that allow …

Scaling up digital circuit computation with DNA strand displacement cascades

L Qian, E Winfree - science, 2011 - science.org
To construct sophisticated biochemical circuits from scratch, one needs to understand how
simple the building blocks can be and how robustly such circuits can scale up. Using a …

Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2. 0

J Schellenberger, R Que, RMT Fleming, I Thiele… - Nature protocols, 2011 - nature.com
Over the past decade, a growing community of researchers has emerged around the use of
constraint-based reconstruction and analysis (COBRA) methods to simulate, analyze and …