The 1921 discovery of insulin was a Big Bang from which a vast and expanding universe of
research into insulin action and resistance has issued. In the intervening century, some …

In order to ensure normal body function, the human body is dependent on a tight control of
its blood glucose levels. This is accomplished by a highly sophisticated network of various …

Covering: up to May 2010 This review (with 335 references cited) is devoted to pentacyclic
triterpenes. The total synthesis, semi-synthesis, structural modification, and metabolic …

Liver glycogen is synthesized after a meal in response to an increase in blood glucose
concentration in the portal vein and endocrine and neuroendocrine signals, and is degraded …

Fish have provided essential information about the structure, biosynthesis, evolution, and
function of insulin (INS) as well as about the structure, evolution, and mechanism of action of …

The liver plays a key role in glucose homeostasis, lipid and energy metabolism. Its function
is primarily controlled by the anabolic hormone insulin and its counterparts glucagon …

Insulin governs systemic glucose metabolism, including glycolysis, gluconeogenesis and
glycogenesis, through temporal change and absolute concentration. However, how insulin …

Purpose: Insulin-like growth factor-I receptor and phosphoinositide 3-kinase/AKT/
mammalian target of rapamycin pathways are among the most active areas of drug …

Recently, we have proposed that quinoa yoghurt (QY) has the anti-diabetic properties based
on an in vitro study. Here, its antidiabetic activity was further validated by investigating its …

The flavonoids quercetin (QUE) and (−)-epigallocatechin-3-gallate (EGCG) are discussed as
potential chemopreventive food constituents. Both compounds have been shown to affect a …