Physics of cell adhesion: some lessons from cell-mimetic systems
E Sackmann, AS Smith - Soft matter, 2014 - pubs.rsc.org
Cell adhesion is a paradigm of the ubiquitous interplay of cell signalling, modulation of
material properties and biological functions of cells. It is controlled by competition of short …
material properties and biological functions of cells. It is controlled by competition of short …
Adhesion of membranes via receptor–ligand complexes: Domain formation, binding cooperativity, and active processes
Cell membranes interact via anchored receptor and ligand molecules. Central questions on
cell adhesion concern the binding affinity of these membrane-anchored molecules, the …
cell adhesion concern the binding affinity of these membrane-anchored molecules, the …
Cooperativity between trans and cis interactions in cadherin-mediated junction formation
Intercellullar junctions formed by cadherins, including desmosomes and adherens junctions,
comprise two dimensional arrays of “trans” dimers formed between monomers emanating …
comprise two dimensional arrays of “trans” dimers formed between monomers emanating …
Kinetics of membrane adhesion mediated by ligand–receptor interaction studied with a biomimetic system
A Boulbitch, Z Guttenberg, E Sackmann - Biophysical Journal, 2001 - cell.com
We report the first measurement of the kinetics of adhesion of a single giant vesicle
controlled by the competition between membrane–substrate interaction mediated by ligand …
controlled by the competition between membrane–substrate interaction mediated by ligand …
The role of binder mobility in spontaneous adhesive contact and implications for cell adhesion
LB Freund, Y Lin - Journal of the Mechanics and Physics of Solids, 2004 - Elsevier
The standard view of mechanical adhesive contact is as a competition between a reduction
in free energy when surfaces with bonding potential come into contact and an increase in …
in free energy when surfaces with bonding potential come into contact and an increase in …
Binding constants of membrane-anchored receptors and ligands: A general theory corroborated by Monte Carlo simulations
Adhesion processes of biological membranes that enclose cells and cellular organelles are
essential for immune responses, tissue formation, and signaling. These processes depend …
essential for immune responses, tissue formation, and signaling. These processes depend …
Growth and shape stability of a biological membrane adhesion complex in the diffusion-mediated regime
VB Shenoy, LB Freund - Proceedings of the National …, 2005 - National Acad Sciences
We examine the process of expansion of a focal adhesion complex by which a biological
membrane containing mobile binders adheres to a substrate with complementary binders …
membrane containing mobile binders adheres to a substrate with complementary binders …
Theoretical concepts and models of cellular mechanosensing
Recent discoveries have established that mechanical properties of the cellular environment
such as its rigidity, geometry, and external stresses play an important role in determining the …
such as its rigidity, geometry, and external stresses play an important role in determining the …
Supported membranes on chemically structured and rough surfaces
We present a general linear response description of membrane adhesion at rough or
chemically structured surfaces. Our method accounts for nonlocal Van der Waals effects and …
chemically structured surfaces. Our method accounts for nonlocal Van der Waals effects and …
Segregation of receptor–ligand complexes in cell adhesion zones: phase diagrams and the role of thermal membrane roughness
The adhesion zone of immune cells, the'immunological synapse', exhibits characteristic
domains of receptor–ligand complexes. The domain formation is probably caused by a …
domains of receptor–ligand complexes. The domain formation is probably caused by a …