Predictors of disease progression in HIV infection: a review

SE Langford, J Ananworanich, DA Cooper - AIDS research and therapy, 2007 - Springer
During the extended clinically latent period associated with Human Immunodeficiency Virus
(HIV) infection the virus itself is far from latent. This phase of infection generally comes to an …

Pharmacogenetics of antiretrovirals

V Tozzi - Antiviral research, 2010 - Elsevier
The introduction of highly active antiretroviral therapy (HAART) as standard of care has
changed the natural history of HIV infection into a manageable chronic disease requiring …

The WHO public-health approach to antiretroviral treatment against HIV in resource-limited settings

CF Gilks, S Crowley, R Ekpini, S Gove, J Perriens… - The lancet, 2006 - thelancet.com
WHO has proposed a public-health approach to antiretroviral therapy (ART) to enable
scaling-up access to treatment for HIV-positive people in develo** countries, recognising …

Highly active antiretroviral therapy and the incidence of non–AIDS-defining cancers in people with HIV infection

T Powles, D Robinson, J Stebbing… - Journal of Clinical …, 2009 - ascopubs.org
Purpose The effect of highly active antiretroviral therapy (HAART) on the incidence of non–
AIDS-defining cancers (NADCs) is unclear. Methods We have investigated the occurrence of …

HIV viral load monitoring in resource-limited regions: optional or necessary?

A Calmy, N Ford, B Hirschel… - Clinical infectious …, 2007 - academic.oup.com
Although it is a standard practice in high-income countries, determination of the human
immunodeficiency virus (HIV) load is not recommended in develo** countries because of …

Patients' perceptions of highly active antiretroviral therapy in relation to treatment uptake and adherence: the utility of the necessity-concerns framework

R Horne, V Cooper, G Gellaitry, HL Date… - JAIDS Journal of …, 2007 - journals.lww.com
Objective: To test the utility of the necessity-concerns framework in predicting highly active
antiretroviral therapy (HAART) uptake and adherence. Methods: This was a prospective …

Tenofovir disoproxil fumarate, emtricitabine, and efavirenz versus fixed-dose zidovudine/lamivudine and efavirenz in antiretroviral-naive patients: virologic …

AL Pozniak, JE Gallant, E DeJesus… - JAIDS Journal of …, 2006 - journals.lww.com
Background: In antiretroviral-naive patients, tenofovir disoproxil fumarate (TDF),
emtricitabine (FTC), and efavirenz (EFV) demonstrated superior outcomes compared with …

CD4 cell counts of 800 cells/mm3 or greater after 7 years of highly active antiretroviral therapy are feasible in most patients starting with 350 cells/mm3 or greater

L Gras, AM Kesselring, JT Griffin… - JAIDS Journal of …, 2007 - journals.lww.com
Objective: CD4 cell count changes in therapy-naive patients were investigated during 7
years of highly active antiretroviral therapy (HAART) in an observational cohort. Methods …

Lopinavir/ritonavir: a review of its use in the management of HIV infection

V Oldfield, GL Plosker - Drugs, 2006 - Springer
Coformulated lopinavir/ritonavir (Kaletra®) is a boosted protease inhibitor (PI) containing
lopinavir and low-dose ritonavir. It is approved for use in combination with other antiretroviral …

HPLC–MS method for the simultaneous quantification of the new HIV protease inhibitor darunavir, and 11 other antiretroviral agents in plasma of HIV-infected patients

A D'Avolio, M Siccardi, M Sciandra, B Lorena… - … of Chromatography B, 2007 - Elsevier
A new method using high performance liquid chromatography coupled with electrospray
mass spectrometry (HPLC–MS) was developed and validated, for the quantification of …