Acute respiratory distress syndrome (ARDS) is a major cause of hypoxemic respiratory
failure in adults, leading to the requirement for mechanical ventilation and poorer outcomes …

The Coronavirus Disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome
Coronavirus 2 (SARS-CoV-2) and its sublineages pose a new challenge to healthcare …

Cellular metabolism is a critical regulator of macrophage effector function. Tissue-resident
alveolar macrophages (TR-AMs) inhabit a unique niche marked by high oxygen and low …

Introduction SARS coronavirus 2 (SARS-CoV-2) infects human angiotensin-converting
enzyme 2 (hACE2)-expressing lung epithelial cells through its spike (S) protein. The S …

The global scope and scale of the SARS-CoV-2 pandemic led to huge amounts of important
data from clinical observations and experimental analyses being collected, in particular …

To standardize metabolomics data analysis and facilitate future computational
developments, it is essential to have a set of well-defined templates for common data …

There is an urgent need to understand severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2)-host interactions involved in virus spread and pathogenesis, which might …

Pulmonary surfactant (PS), a complex mixture of lipids and proteins, is essential for
maintaining proper lung function. It reduces surface tension in the alveoli, preventing …

Viruses are obligate intracellular parasites, and they exploit the cellular pathways and
resources of their respective host cells to survive and successfully multiply. The strategies of …

Pulmonary surfactant has been attempted as a supportive therapy to treat COVID-19.
Although it is mechanistically accepted that the fusion peptide in the S2 subunit of the S …