Metabolic engineering: methodologies and applications

MJ Volk, VG Tran, SI Tan, S Mishra, Z Fatma… - Chemical …, 2022 - ACS Publications
Metabolic engineering aims to improve the production of economically valuable molecules
through the genetic manipulation of microbial metabolism. While the discipline is a little over …

Systems metabolic engineering of microorganisms for food and cosmetics production

KR Choi, SY Lee - Nature Reviews Bioengineering, 2023 - nature.com
The demand for sustainable and environmentally friendly sources of foods and cosmetics is
increasing owing to concerns about the rapid growth of the global population and climate …

The ModelSEED Biochemistry Database for the integration of metabolic annotations and the reconstruction, comparison and analysis of metabolic models for plants …

SMD Seaver, F Liu, Q Zhang, J Jeffryes… - Nucleic acids …, 2021 - academic.oup.com
For over 10 years, ModelSEED has been a primary resource for the construction of draft
genome-scale metabolic models based on annotated microbial or plant genomes. Now …

Emerging technologies for conversion of sustainable algal biomass into value-added products: A state-of-the-art review

K Zhang, F Zhang, YR Wu - Science of the Total Environment, 2021 - Elsevier
Concerns regarding high energy demand and gradual depletion of fossil fuels have
attracted the desire of seeking renewable and sustainable alternatives. Similar to but better …

Designing the bioproduction of Martian rocket propellant via a biotechnology-enabled in situ resource utilization strategy

NS Kruyer, MJ Realff, W Sun, CL Genzale… - Nature …, 2021 - nature.com
Mars colonization demands technological advances to enable the return of humans to Earth.
Ship** the propellant and oxygen for a return journey is not viable. Considering the …

New trends and perspectives in production of 1, 2-propanediol

M Główka, T Krawczyk - ACS Sustainable Chemistry & …, 2023 - ACS Publications
The production of 1, 2-propanediol is a significant challenge for the chemical industry due to
the increasing demand for this versatile product and the pro-ecological regulatory actions …

A comprehensive review on microbial production of 1, 2-propanediol: Micro-organisms, metabolic pathways, and metabolic engineering

Y Tao, C Bu, L Zou, Y Hu, ZJ Zheng, J Ouyang - Biotechnology for Biofuels, 2021 - Springer
Propanediol is an important building block as a component used in the manufacture of
unsaturated polyester resin, antifreeze, biofuel, nonionic detergent, etc. Commercial …

[HTML][HTML] Optimizing microbial networks through metabolic bypasses

E Orsi, NJ Claassens, PI Nikel, SN Lindner - Biotechnology Advances, 2022 - Elsevier
Metabolism has long been considered as a relatively stiff set of biochemical reactions. This
somewhat outdated and dogmatic view has been challenged over the last years, as multiple …

Direct biosynthesis of adipic acid from lignin-derived aromatics using engineered Pseudomonas putida KT2440

W Niu, H Willett, J Mueller, X He, L Kramer, B Ma… - Metabolic …, 2020 - Elsevier
Lignin is one largely untapped natural resource that can be exploited as a raw material for
the bioproduction of value-added chemicals. Meanwhile, the current petroleum-based …

Revealing the Characteristics of Glucose- and Lactate-Based Chain Elongation for Caproate Production by Caproicibacterium lactatifermentans through …

H Wang, W Zhou, J Gao, C Ren, Y Xu - Msystems, 2022 - Am Soc Microbiol
Caproate, an important medium-chain fatty acid, can only be synthesized by limited bacterial
species by using ethanol, lactate, or certain saccharides. Caproicibacterium …