Deep downregulation of PD‐L1 by caged peptide‐conjugated AIEgen/miR‐140 nanoparticles for enhanced immunotherapy

J Dai, JJ Hu, X Dong, B Chen, X Dong… - Angewandte Chemie …, 2022 - Wiley Online Library
Downregulating programmed cell death ligand 1 (PD‐L1) protein levels in tumor cells is an
effective way to achieve immune system activation for oncology treatment, but current …

Smooth modified surfaces of silicon for the study of ionic liquid interfaces by neutron reflectometry

JM Klein, H Wang, RL Sacci, JF Browning… - ACS Applied …, 2022 - ACS Publications
Silicon surfaces with termination of hydrogen (H–Si), quartz, native silicon (native-Si), and
chemically deposited (Au–Si) cd and sputtered gold (Au–Si) s were fabricated with …

Formation and characterization of a stable monolayer of active acetylcholinesterase on planar gold

JM Correira, LJ Webb - Langmuir, 2022 - ACS Publications
Enzyme activity is the basis for many biosensors where a catalytic event is used to detect the
presence and amount of a biomolecule of interest. To create a practical point-of-care …

[HTML][HTML] Role of hydrophobic side chain in urea induced protein denaturation at interface

P Gahtori, V Gunwant, R Pandey - Chemical Physics Impact, 2023 - Elsevier
The molecular mechanism of denaturing ability of urea is still a subject of considerable
debate due to two opposing mechanisms: direct and indirect. In the direct mechanism, urea …

Hydration of a 2D supramolecular assembly: Bitartrate on Cu (110)

C Lin, GR Darling, M Forster, F McBride… - Journal of the …, 2020 - ACS Publications
Hydration layers play a key role in many technical and biological systems, but our
understanding of these structures remains very limited. Here, we investigate the molecular …

Thermally Driven Transformation of Water Clustering Structures at Self-Assembled Monolayers

Y Liu, XH **a - Langmuir, 2021 - ACS Publications
Water clustering structures are considered to play key roles in various temperature-
dependent life activities. However, our fundamental understanding of the temperature …

Measuring the Multiscale Dynamics, Structure, and Function of Biomolecules at Interfaces

R Noriega - The Journal of Physical Chemistry B, 2021 - ACS Publications
The individual and collective structure and properties of biomolecules can change
dramatically when they are localized at an interface. However, the small spatial extent of …

Enzyme immobilization on gold surfaces: effects of surface chemistry and attachment strategies on binding and activity

JM Correira - 2023 - repositories.lib.utexas.edu
Functional enzymes are the basis for many biotechnological systems, including biosensors,
bio-fuel cells, and heterogeneous biocatalysts. In these systems, enzymes are often …