The normal development and maintenance of the prostate is dependent on androgen acting
through the androgen receptor (AR). AR remains important in the development and …

The androgen receptor (AR), ligand-induced transcription factor, is expressed in primary
prostate cancer and in metastases. AR regulates multiple cellular events, proliferation …

Transforming growth factor-beta (TGF-β) is a multifunctional cytokine, whose numerous cell
and tissue activities include cell-cycle control, the regulation of early development …

Dermal papilla cells (DPCs) taken from male androgenetic alopecia (AGA) patients undergo
premature senescence in vitro in association with the expression of p16 INK4a, suggesting …

Cells possess within their epigenetic repertoire the ability to undergo an active process of
cellular suicide termed programmed (or apoptotic) cell death. This programmed cell death …

This report describes the development and characterization of an epithelial cell line (BPH-1)
from human prostate tissue obtained by transurethral resection. Primary epithelial cell …

BACKGROUND Prostate tumors express high levels of transforming growth factor‐β1 (TGF‐
β1) and seem to acquire resistance to its antiproliferative effects with tumor progression …

We have examined the hypothesis that neuronal programmed cell death requires a genetic
program; we used a model wherein rat sympathetic neurons maintained in vitro are deprived …

OBJECTIVE To determine if the levels of circulating myeloid‐derived suppressor cells
increase with progression of prostate cancer (PCa); to determine if such cells could …

In previous studies hepatocytes undergoing cell death by apoptosis but not normal
hepatocytes in rat liver showed immunostaining for transforming growth factor beta 1 (TGF …