I. Executive Summary Background The 5 years since the publication of the first International
Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed …

Over the past two decades, significant progress in understanding of the pathogenesis of type
2 chronic inflammatory diseases has enabled the identification of compounds for more than …

Background Eosinophilic inflammation has been implicated in the pathogenesis, severity,
and treatment responsiveness of chronic rhinosinusitis with nasal polyps (CRSwNP) …

Abstract Purpose of Review Chronic rhinosinusitis (CRS) is a highly prevalent disease with
large social and financial burdens. The pathophysiology is multifactorial. Environmental …

The heterogeneous cellular microenvironment of human airway chronic inflammatory
diseases, including chronic rhinosinusitis (CRS) and asthma, is still poorly understood …

Asthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly
overlap in the human interactome. The concept of “one‐airway‐one‐disease,” coined over …

Chronic rhinosinusitis (CRS) is a common clinical syndrome that produces significant
morbidity and costs to our health system. The study of CRS has progressed from an era …

Knowledge of chronic rhinosinusitis (CRS) epidemiology may directly impact patient care:
aiding patient identification and establishing accurate diagnosis as well as informing …

The European Position Paper on Rhinosinusitis and Nasal Polyps 2020 is the update of
similar evidence based position papers published in 2005 and 2007 and 2012 (1-3). The …

Chronic rhinosinusitis with nasal polyps (CRSwNP) is generally associated with eosinophilic
tissue infiltration linked to type 2 inflammation and characterized by elevated levels of …