Anticancer agents are critical for the cancer treatment, but side effects and the drug
resistance associated with the currently used anticancer agents create an urgent need to …

The development of novel synthetic strategies to form new chemical entities in a
stereoselective manner is an ongoing significant objective in organic and medicinal …

Tuberculosis (TB) remains one of the most widespread and leading deadliest diseases,
threats one-third of the world's population. Although numerous efforts have been undertaken …

Antibiotics are commonly used to fight against bacterial infections, but bacteria have already
been resistant to almost all antibiotics due to abuse of antibiotics. 1, 2, 4-Triazole derived …

Many researchers around the world are working on the development of novel anticancer
drugs with different mechanisms of action. In this case, coumarin is a highly promising …

Malaria, in particular infection with P. falciparum (the most lethal of the human malaria
parasite species, responsible for nearly one million deaths every year), is one of the most …

Malaria, caused by protozoan parasites of the genus Plasmodium especially by the most
prevalent parasite Plasmodium falciparum, represents one of the most devastating and …

Cancer is the second leading cause of death worldwide, and it results in around 9 million
deaths annually. The anticancer agents play an intriguing role in the treatment of cancers …

Isatin (1 H indole 2, 3-dione) is a heterocyclic, endogenous lead molecule recognized in
humans and different plants. The isatin nucleus and its derivatives are owed the attention of …

Quinoline and quinolone motifs which act as structural subunits of more complex natural
products are ubiquitous in nature, and they are useful pharmacophores which play a pivotal …