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Sleep deprivation and neurological disorders
Sleep plays an important role in maintaining neuronal circuitry, signalling and helps
maintain overall health and wellbeing. Sleep deprivation (SD) disturbs the circadian …
maintain overall health and wellbeing. Sleep deprivation (SD) disturbs the circadian …
Can melatonin reduce the severity of COVID-19 pandemic?
The current COVID-19 pandemic is one of the most devastating events in recent history. The
virus causes relatively minor damage to young, healthy populations, imposing life …
virus causes relatively minor damage to young, healthy populations, imposing life …
[HTML][HTML] Sleep loss can cause death through accumulation of reactive oxygen species in the gut
The view that sleep is essential for survival is supported by the ubiquity of this behavior, the
apparent existence of sleep-like states in the earliest animals, and the fact that severe sleep …
apparent existence of sleep-like states in the earliest animals, and the fact that severe sleep …
A review of lifestyle factors that contribute to important pathways associated with major depression: diet, sleep and exercise
Research on major depression has confirmed that it is caused by an array of
biopsychosocial and lifestyle factors. Diet, exercise and sleep are three such influences that …
biopsychosocial and lifestyle factors. Diet, exercise and sleep are three such influences that …
Molecular mechanisms and genetics of oxidative stress in Alzheimer's disease
F Cioffi, RHI Adam, K Broersen - Journal of Alzheimer's …, 2019 - content.iospress.com
Alzheimer's disease is the most common neurodegenerative disorder that can cause
dementia in elderly over 60 years of age. One of the disease hallmarks is oxidative stress …
dementia in elderly over 60 years of age. One of the disease hallmarks is oxidative stress …
Sleep deprivation, oxidative stress and inflammation
Adequate sleep is essential for normal brain function, especially during early life
developmental stages as postnatal brain maturation occurs during the critical period of …
developmental stages as postnatal brain maturation occurs during the critical period of …
Clues to the functions of mammalian sleep
JM Siegel - Nature, 2005 - nature.com
The functions of mammalian sleep remain unclear. Most theories suggest a role for non-
rapid eye movement (NREM) sleep in energy conservation and in nervous system …
rapid eye movement (NREM) sleep in energy conservation and in nervous system …
Statin adverse effects: a review of the literature and evidence for a mitochondrial mechanism
BA Golomb, MA Evans - American Journal of Cardiovascular Drugs, 2008 - Springer
HMG-CoA reductase inhibitors (statins) are a widely used class of drug, and like all
medications, have potential for adverse effects (AEs). Here we review the statin AE literature …
medications, have potential for adverse effects (AEs). Here we review the statin AE literature …
Sleep deprivation and oxidative stress in animal models: a systematic review
Because the function and mechanisms of sleep are partially clear, here we applied a meta‐
analysis to address the issue whether sleep function includes antioxidative properties in …
analysis to address the issue whether sleep function includes antioxidative properties in …
Sleep viewed as a state of adaptive inactivity
JM Siegel - Nature Reviews Neuroscience, 2009 - nature.com
Sleep is often viewed as a vulnerable state that is incompatible with behaviours that nourish
and propagate species. This has led to the hypothesis that sleep has survived because it …
and propagate species. This has led to the hypothesis that sleep has survived because it …