Sleep deprivation and neurological disorders

M Bishir, A Bhat, MM Essa, O Ekpo… - BioMed research …, 2020 - Wiley Online Library
Sleep plays an important role in maintaining neuronal circuitry, signalling and helps
maintain overall health and wellbeing. Sleep deprivation (SD) disturbs the circadian …

Can melatonin reduce the severity of COVID-19 pandemic?

A Shneider, A Kudriavtsev… - International reviews of …, 2020 - Taylor & Francis
The current COVID-19 pandemic is one of the most devastating events in recent history. The
virus causes relatively minor damage to young, healthy populations, imposing life …

[HTML][HTML] Sleep loss can cause death through accumulation of reactive oxygen species in the gut

A Vaccaro, YK Dor, K Nambara, EA Pollina, C Lin… - Cell, 2020 - cell.com
The view that sleep is essential for survival is supported by the ubiquity of this behavior, the
apparent existence of sleep-like states in the earliest animals, and the fact that severe sleep …

A review of lifestyle factors that contribute to important pathways associated with major depression: diet, sleep and exercise

AL Lopresti, SD Hood, PD Drummond - Journal of affective disorders, 2013 - Elsevier
Research on major depression has confirmed that it is caused by an array of
biopsychosocial and lifestyle factors. Diet, exercise and sleep are three such influences that …

Molecular mechanisms and genetics of oxidative stress in Alzheimer's disease

F Cioffi, RHI Adam, K Broersen - Journal of Alzheimer's …, 2019 - content.iospress.com
Alzheimer's disease is the most common neurodegenerative disorder that can cause
dementia in elderly over 60 years of age. One of the disease hallmarks is oxidative stress …

Sleep deprivation, oxidative stress and inflammation

F Atrooz, S Salim - Advances in protein chemistry and structural biology, 2020 - Elsevier
Adequate sleep is essential for normal brain function, especially during early life
developmental stages as postnatal brain maturation occurs during the critical period of …

Clues to the functions of mammalian sleep

JM Siegel - Nature, 2005 - nature.com
The functions of mammalian sleep remain unclear. Most theories suggest a role for non-
rapid eye movement (NREM) sleep in energy conservation and in nervous system …

Statin adverse effects: a review of the literature and evidence for a mitochondrial mechanism

BA Golomb, MA Evans - American Journal of Cardiovascular Drugs, 2008 - Springer
HMG-CoA reductase inhibitors (statins) are a widely used class of drug, and like all
medications, have potential for adverse effects (AEs). Here we review the statin AE literature …

Sleep deprivation and oxidative stress in animal models: a systematic review

G Villafuerte, A Miguel-Puga… - Oxidative medicine …, 2015 - Wiley Online Library
Because the function and mechanisms of sleep are partially clear, here we applied a meta‐
analysis to address the issue whether sleep function includes antioxidative properties in …

Sleep viewed as a state of adaptive inactivity

JM Siegel - Nature Reviews Neuroscience, 2009 - nature.com
Sleep is often viewed as a vulnerable state that is incompatible with behaviours that nourish
and propagate species. This has led to the hypothesis that sleep has survived because it …