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Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6, CYP2C19, CYP2B6, SLC6A4, and HTR2A Genotypes and Serotonin …
Serotonin reuptake inhibitor antidepressants, including selective serotonin reuptake
inhibitors (SSRIs; ie, citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, and …
inhibitors (SSRIs; ie, citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, and …
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Selective Serotonin Reuptake …
Selective serotonin reuptake inhibitors (SSRIs) are primary treatment options for major
depressive and anxiety disorders. CYP2D6 and CYP2C19 polymorphisms can influence the …
depressive and anxiety disorders. CYP2D6 and CYP2C19 polymorphisms can influence the …
Clinical pharmacogenetics implementation consortium guideline (CPIC®) for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants: 2016 update
CYP2D6 and CYP2C19 polymorphisms affect the exposure, efficacy and safety of tricyclic
antidepressants (TCAs), with some drugs being affected by CYP2D6 only (eg, nortriptyline …
antidepressants (TCAs), with some drugs being affected by CYP2D6 only (eg, nortriptyline …
Association of CYP2C19 and CYP2D6 poor and intermediate metabolizer status with antidepressant and antipsychotic exposure: a systematic review and meta …
F Milosavljević, N Bukvić, Z Pavlović, Č Miljević… - JAMA …, 2021 - jamanetwork.com
Importance Precise estimation of the drug metabolism capacity for individual patients is
crucial for adequate dose personalization. Objective To quantify the difference in the …
crucial for adequate dose personalization. Objective To quantify the difference in the …
Peripheral biomarkers of major depression and antidepressant treatment response: current knowledge and future outlooks
Background In recent years, we have accomplished a deeper understanding about the
pathophysiology of major depressive disorder (MDD). Nevertheless, this improved …
pathophysiology of major depressive disorder (MDD). Nevertheless, this improved …
Impact of CYP2C19 metaboliser status on SSRI response: a retrospective study of 9500 participants of the Australian Genetics of Depression Study
Background Variation within the CYP2C19 gene has been linked to differential metabolism
of selective serotonin reuptake inhibitors (SSRIs). Pharmacogenetic recommendations …
of selective serotonin reuptake inhibitors (SSRIs). Pharmacogenetic recommendations …
[HTML][HTML] Pharmacogenomics in psychiatry practice: the value and the challenges
A Alchakee, M Ahmed, L Eldohaji, H Alhaj… - International journal of …, 2022 - mdpi.com
The activity of cytochrome P450 enzymes is influenced by genetic and nongenetic factors;
hence, the metabolism of exogenous psychotropic medications and potentially some …
hence, the metabolism of exogenous psychotropic medications and potentially some …
[HTML][HTML] Influence of CYP2C19 metabolizer status on escitalopram/citalopram tolerability and response in youth with anxiety and depressive disorders
SL Aldrich, EA Poweleit, CA Prows, LJ Martin… - Frontiers in …, 2019 - frontiersin.org
In pediatric patients, the selective serotonin reuptake inhibitors (SSRIs) escitalopram and
citalopram (es/citalopram) are commonly prescribed for anxiety and depressive disorders …
citalopram (es/citalopram) are commonly prescribed for anxiety and depressive disorders …
Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: Meta-analysis of data from genome-wide association studies
Cytochrome (CYP) P450 enzymes have a primary role in antidepressant metabolism and
variants in these polymorphic genes are targets for pharmacogenetic investigation. This is …
variants in these polymorphic genes are targets for pharmacogenetic investigation. This is …
Metabolic activity of CYP2C19 and CYP2D6 on antidepressant response from 13 clinical studies using genotype imputation: a meta-analysis
Cytochrome P450 enzymes including CYP2C19 and CYP2D6 are important for
antidepressant metabolism and polymorphisms of these genes have been determined to …
antidepressant metabolism and polymorphisms of these genes have been determined to …