2024 heart disease and stroke statistics: a report of US and global data from the American Heart Association

SS Martin, AW Aday, ZI Almarzooq, CAM Anderson… - Circulation, 2024 - Am Heart Assoc
BACKGROUND: The American Heart Association (AHA), in conjunction with the National
Institutes of Health, annually reports the most up-to-date statistics related to heart disease …

Heart disease and stroke statistics—2022 update: a report from the American Heart Association

CW Tsao, AW Aday, ZI Almarzooq, A Alonso… - Circulation, 2022 - Am Heart Assoc
Background: The American Heart Association, in conjunction with the National Institutes of
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …

[HTML][HTML] Situación actual de la obesidad infantil en México

A Pérez-Herrera, M Cruz-López - Nutrición hospitalaria, 2019 - SciELO Espana
México ha reportado en el año 2016 una prevalencia combinada de obesidad y sobrepeso
del 33, 2% en niños. El objetivo de este trabajo fue hacer una revisión bibliográfica de los …

Heart disease and stroke statistics—2023 update: a report from the American Heart Association

CW Tsao, AW Aday, ZI Almarzooq, CAM Anderson… - Circulation, 2023 - Am Heart Assoc
Background: The American Heart Association, in conjunction with the National Institutes of
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …

The genetics of obesity: from discovery to biology

RJF Loos, GSH Yeo - Nature Reviews Genetics, 2022 - nature.com
The prevalence of obesity has tripled over the past four decades, imposing an enormous
burden on people's health. Polygenic (or common) obesity and rare, severe, early-onset …

Interpreting type 1 diabetes risk with genetics and single-cell epigenomics

J Chiou, RJ Geusz, ML Okino, JY Han, M Miller… - Nature, 2021 - nature.com
Genetic risk variants that have been identified in genome-wide association studies of
complex diseases are primarily non-coding. Translating these risk variants into mechanistic …

Benefits and limitations of genome-wide association studies

V Tam, N Patel, M Turcotte, Y Bossé, G Paré… - Nature Reviews …, 2019 - nature.com
Genome-wide association studies (GWAS) involve testing genetic variants across the
genomes of many individuals to identify genotype–phenotype associations. GWAS have …

Reading Mendelian randomisation studies: a guide, glossary, and checklist for clinicians

NM Davies, MV Holmes, GD Smith - bmj, 2018 - bmj.com
Mendelian randomisation uses genetic variation as a natural experiment to investigate the
causal relations between potentially modifiable risk factors and health outcomes in …

Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria

F Day, T Karaderi, MR Jones, C Meun, C He… - PLoS …, 2018 - journals.plos.org
Polycystic ovary syndrome (PCOS) is a disorder characterized by hyperandrogenism,
ovulatory dysfunction and polycystic ovarian morphology. Affected women frequently have …

Use of genetic variation to separate the effects of early and later life adiposity on disease risk: mendelian randomisation study

TG Richardson, E Sanderson, B Elsworth, K Tilling… - Bmj, 2020 - bmj.com
Objective To evaluate whether body size in early life has an independent effect on risk of
disease in later life or whether its influence is mediated by body size in adulthood. Design …