Candidate pathways for retina to scleral signaling in refractive eye growth
The global prevalence of myopia, or nearsightedness, has increased at an alarming rate
over the last few decades. An eye is myopic if incoming light focuses prior to reaching the …
over the last few decades. An eye is myopic if incoming light focuses prior to reaching the …
RPE and choroid mechanisms underlying ocular growth and myopia
Y Zhang, CF Wildsoet - Progress in molecular biology and translational …, 2015 - Elsevier
Myopia is the most common type of refractive errors and one of the world's leading causes of
blindness. Visual manipulations in animal models have provided convincing evidence for …
blindness. Visual manipulations in animal models have provided convincing evidence for …
Expression of pro-angiogenic markers is enhanced by blue light in human RPE cells
C Scimone, S Alibrandi, SZ Scalinci… - Antioxidants, 2020 - mdpi.com
Inherited retinal dystrophies are characterized by photoreceptor death. Oxidative stress
usually occurs, increasing vision loss, and oxidative damage is often reported in retinitis …
usually occurs, increasing vision loss, and oxidative damage is often reported in retinitis …
Defocus-induced spatial changes in choroidal thickness of chicks observed by wide-field swept-source OCT
Y Huang, Y Wang, Y Shen, Z Chen, X Peng… - Experimental Eye …, 2023 - Elsevier
Choroid has been claimed to be of importance during ocular development. However, how
the choroid responds spatially to different visual cues has not been fully understood. The …
the choroid responds spatially to different visual cues has not been fully understood. The …
Bidirectional expression of metabolic, structural, and immune pathways in early myopia and hyperopia
Myopia (short-sightedness) affects 1.45 billion people worldwide, many of whom will
develop sight-threatening secondary disorders. Myopic eyes are characterized by excessive …
develop sight-threatening secondary disorders. Myopic eyes are characterized by excessive …
[HTML][HTML] A hypothesis for treating inflammation and oxidative stress with hydrogen sulfide during age-related macular degeneration
AK George, M Singh, RP Homme… - International journal …, 2018 - ncbi.nlm.nih.gov
Age-related macular degeneration (AMD) is a leading cause of blindness and is becoming a
global crisis since affected people will increase to 288 million by 2040. Genetics, age …
global crisis since affected people will increase to 288 million by 2040. Genetics, age …
The role of retinal dysfunction in myopia development
Y Huang, X Chen, J Zhuang, K Yu - Cellular and Molecular Neurobiology, 2023 - Springer
Myopia is a refractive disorder arising from a mismatch between refractive power and
relatively long axial length of the eye. With its dramatically increasing prevalence, myopia …
relatively long axial length of the eye. With its dramatically increasing prevalence, myopia …
Pathway analysis identifies altered mitochondrial metabolism, neurotransmission, structural pathways and complement cascade in retina/RPE/choroid in chick model …
Purpose RNA sequencing analysis has demonstrated bidirectional changes in metabolism,
structural and immune pathways during early induction of defocus induced myopia. Thus …
structural and immune pathways during early induction of defocus induced myopia. Thus …
Sensing through non-sensing ocular ion channels
Ion channels are membrane-spanning integral proteins expressed in multiple organs,
including the eye. In the eye, ion channels are involved in various physiological processes …
including the eye. In the eye, ion channels are involved in various physiological processes …
Role of hydrogen sulfide in retinal diseases
J Du, H **, L Yang - Frontiers in Pharmacology, 2017 - frontiersin.org
As the third gasotransmitter, hydrogen sulfide (H2S) plays a crucial role in the physiology
and pathophysiology of many systems in the body, such as the nervous, cardiovascular …
and pathophysiology of many systems in the body, such as the nervous, cardiovascular …