Inflammation is an integral part of autoimmune diseases, which are caused by dysregulation
of the immune system. This dysregulation involves an imbalance between pro-inflammatory …

Colorectal cancer (CRC) is one of the most common malignant carcinomas. CRC is
characterized by asymptomatic onset, and most patients are already in the middle and …

Bark protects the tree against environmental insults. Here, we analyzed whether this
defensive strategy could be utilized to broadly enhance protection against colitis. As a proof …

Sirtuins are nicotinamide adenine dinucleotide (NAD+)-dependent deacylases that have
traditionally been linked with calorie restriction and aging in mammals. These proteins also …

Neurodegenerative diseases are characterized by the loss of neurons and/or myelin sheath,
which deteriorate over time and cause dysfunction. Interleukin 17A is the signature cytokine …

Resveratrol (3, 5, 4'-trihydroxy-trans-stilbene) is a non-flavonoid polyphenol that may be
present in a limited number of foodstuffs such as grapes and red wine. Resveratrol has been …

BACKGROUND & AIMS: The pathogenesis of inflammatory bowel disease (IBD) is believed
to involve an altered balance between effector and regulatory T cells. Aryl hydrocarbon …

Flavonoids are a family of polyphenolic compounds which are widespread in nature
(vegetables) and are consumed as part of the human diet in significant amounts. There are …

Lung cancer (LC) is the leading cause of cancer-related death worldwide due to its late
diagnosis and poor outcomes. As has been found for other types of tumors, there is …

Flavonoid resveratrol modulates the transcription factor NF-κB; inhibits the cytochrome P450
isoenzyme CYP1 A1; suppresses the expression and activity of cyclooxygenase enzymes; …