Role of exosomal non-coding RNAs from tumor cells and tumor-associated macrophages in the tumor microenvironment

Z Xu, Y Chen, L Ma, Y Chen, J Liu, Y Guo, T Yu… - Molecular Therapy, 2022‏ - cell.com
Exosomes have a crucial role in intercellular communication and mediate interactions
between tumor cells and tumor-associated macrophages (TAMs). Exosome-encapsulated …

[HTML][HTML] Prognostic and predictive biomarkers in gliomas

P Śledzińska, MG Bebyn, J Furtak… - International journal of …, 2021‏ - mdpi.com
Gliomas are the most common central nervous system tumors. New technologies, including
genetic research and advanced statistical methods, revolutionize the therapeutic approach …

The regulatory role of micro RNA s in angiogenesis‐related diseases

LL Sun, WD Li, FR Lei, XQ Li - Journal Of Cellular And …, 2018‏ - Wiley Online Library
Micro RNA s (mi RNA s) are small non‐coding RNA s that regulate gene expression at a
post‐transcriptional level via either the degradation or translational repression of a target …

Extracellular vesicles in glioblastoma tumor microenvironment

A Yekula, A Yekula, K Muralidharan, K Kang… - Frontiers in …, 2020‏ - frontiersin.org
Glioblastomas (GBM) are highly aggressive primary brain tumors. Complex and dynamic
tumor microenvironment (TME) plays a crucial role in the sustained growth, proliferation, and …

Artificial intelligence and precision medicine: a new frontier for the treatment of brain tumors

AK Philip, BA Samuel, S Bhatia, SAM Khalifa… - Life, 2022‏ - mdpi.com
Brain tumors are a widespread and serious neurological phenomenon that can be life-
threatening. The computing field has allowed for the development of artificial intelligence …

[HTML][HTML] The roles of miRNA in glioblastoma tumor cell communication: diplomatic and aggressive negotiations

A Buruiană, ȘI Florian, AI Florian, TL Timiș… - International journal of …, 2020‏ - mdpi.com
Glioblastoma (GBM) consists of a heterogeneous collection of competing cellular clones
which communicate with each other and with the tumor microenvironment (TME) …

A microRNA signature from serum exosomes of patients with glioma as complementary diagnostic biomarker

A Santangelo, P Imbrucè, B Gardenghi, L Belli… - Journal of neuro …, 2018‏ - Springer
Malignant gliomas, the most frequent primary brain tumors, are characterized by a dismal
prognosis. Reliable biomarkers complementary to neuroradiology in the differential …

[HTML][HTML] Liquid biopsy in glioblastoma

L Ronvaux, M Riva, A Coosemans, M Herzog… - Cancers, 2022‏ - mdpi.com
Simple Summary Glioblastoma is the most common and malignant primary brain tumor.
Despite intensive research for new treatments, the survival of patients has not significantly …

Liquid biopsy in glioblastoma management: from current research to future perspectives

L Gatto, E Franceschi, V Di Nunno, A Tosoni… - The …, 2021‏ - academic.oup.com
Glioblastoma (GBM) is the most common primary tumor of the central nervous system.
Arising from neuroepithelial glial cells, GBM is characterized by invasive behavior, extensive …

Hypoxic cancer-secreted exosomal miR-182-5p promotes glioblastoma angiogenesis by targeting Kruppel-like factor 2 and 4

J Li, H Yuan, H Xu, H Zhao, N **ong - Molecular Cancer Research, 2020‏ - aacrjournals.org
Glioblastoma (GBM) is the most lethal primary brain tumor and has a complex molecular
profile. Hypoxia plays a critical role during tumor progression and in the tumor …