Mature microRNAs (miRNAs) are a class of evolutionally conserved, single-stranded, small
(approximately 19− 23 nucleotides), endogenously expressed, and non-protein-coding …

Photodynamic therapy (PDT) is a minimally invasive treatment that destroys target cells in
the presence of oxygen when light irradiates a photosensitizer, generating highly reactive …

Control of CRISPR/Cas12a trans-cleavage is crucial for biosensor development. Here, we
show that small circular DNA nanostructures which partially match guide RNA sequences …

The success of fluorescence experiments requires attention to experimental details and an
understanding of the instrumentation. There are also many potential artifacts that can distort …

DNA is increasingly being used as the engineering material of choice for the construction of
nanoscale circuits, structures, and motors. Many of these enzyme-free constructions function …

Artificial biochemical circuits are likely to play as large a role in biological engineering as
electrical circuits have played in the engineering of electromechanical devices. Toward that …

The field of fluorogenic RNA aptamers is a burgeoning research area that aims to address
the lack of naturally fluorescent RNA molecules for RNA detection and imaging. These small …

Fluorescence is the most popular technique in chemical and biological sensing because of
its ultimate sensitivity, high temporal and spatial resolution and versatility that enables …

This review highlights various methods that can be used for a sensitive detection of nucleic
acids without using thermal cycling procedures, as is done in PCR or LCR. Topics included …

Photoelectrochemical (PEC) water reduction, converting solar energy into environmentally
friendly hydrogen fuel, requires delicate design and synthesis of semiconductors with …