Recent progress in aptamer discoveries and modifications for therapeutic applications

S Ni, Z Zhuo, Y Pan, Y Yu, F Li, J Liu… - … Applied Materials & …, 2020 - ACS Publications
Aptamers are oligonucleotide sequences with a length of about 25–80 bases which have
abilities to bind to specific target molecules that rival those of monoclonal antibodies. They …

Advances in single-component inorganic nanostructures for photoacoustic imaging guided photothermal therapy

H Zhu, B Li, CY Chan, BLQ Ling, J Tor, XY Oh… - Advanced Drug Delivery …, 2023 - Elsevier
Phototheranostic based on photothermal therapy (PTT) and photoacoustic imaging (PAI), as
one of avant-garde medical techniques, have sparked growing attention because it allows …

Fabrication of chitosan-gelatin films incorporated with thymol-loaded alginate microparticles for controlled drug delivery, antibacterial activity and wound healing: in …

AR Ahmady, K Razmjooee, S Saber-Samandari… - International Journal of …, 2022 - Elsevier
Previously, studies have demonstrated the unique characteristics of chitosan-gelatin films as
wound dressings applications. However, their application has been limited due to their …

[HTML][HTML] Therapeutic aptamer targeting sclerostin loop3 for promoting bone formation without increasing cardiovascular risk in osteogenesis imperfecta mice

L Wang, Y Yu, S Ni, D Li, J Liu, D **e, HY Chu… - Theranostics, 2022 - ncbi.nlm.nih.gov
Rationale: Sclerostin inhibition demonstrated bone anabolic potential in osteogenesis
imperfecta (OI) mice, whereas humanized therapeutic sclerostin antibody romosozumab for …

The neuroprotective effects of fisetin, a natural flavonoid in neurodegenerative diseases: Focus on the role of oxidative stress

SS Hassan, S Samanta, R Dash… - Frontiers in …, 2022 - frontiersin.org
Oxidative stress (OS) disrupts the chemical integrity of macromolecules and increases the
risk of neurodegenerative diseases. Fisetin is a flavonoid that exhibits potent antioxidant …

Multipurpose properties the Z-scheme dimanganese copper oxide/cadmium sulfide nanocomposites for photo-or photoelectro-catalytic, antibacterial applications, and …

X Yao, YJ BahrAluloom, SF Jawad… - … of Photochemistry and …, 2023 - Elsevier
Cadmium sulfide improved with dimanganese copper oxide (Mn 2 CuO 4/CdO) was
prepared and applied this semiconductor nanocomposites in advanced oxidative processes …

Fabrication of novel rational Ti-Sn doped Cu-ferrite nanoparticles for robust photocatalysis reaction, magnetic resonance imaging, and chemo-magneto-photo-thermal …

B Hu, Y Cui, X Yang, X Xu, BJ Janani, A Fakhri - Surfaces and Interfaces, 2022 - Elsevier
This project presents the novel synthesize of the Ti-Sn doped Cu-ferrite nanoparticles with
different ratios by sol gel/precipitation rout. The main properties of Ti 0.5-x Sn x Cu 0.5 Fe 2 …

Improved deep convolutional neural networks using chimp optimization algorithm for Covid19 diagnosis from the X-ray images

C Cai, B Gou, M Khishe, M Mohammadi… - Expert Systems with …, 2023 - Elsevier
Abstract Applying Deep Learning (DL) in radiological images (ie, chest X-rays) is emerging
because of the necessity of having accurate and fast COVID-19 detectors. Deep …

Targeting loop3 of sclerostin preserves its cardiovascular protective action and promotes bone formation

Y Yu, L Wang, S Ni, D Li, J Liu, HY Chu… - Nature …, 2022 - nature.com
Sclerostin negatively regulates bone formation by antagonizing Wnt signalling. An antibody
targeting sclerostin for the treatment of postmenopausal osteoporosis was approved by the …

Influence of the coiling porosity on the risk reduction of the cerebral aneurysm rupture: Computational study

A Sheidani, M Barzegar Gerdroodbary, A Poozesh… - Scientific reports, 2022 - nature.com
The formation and progress of cerebral aneurysm is highly associated with hemodynamic
factors and blood flow feature. In this study, comprehensive efforts are done to investigate …